How is insulin‑like growth factor‑1 correlated with retinopathy of prematurity?
Evaluation of insulin‑like growth factor‑1 (IGF‑1) association with retinopathy of prematurity (ROP) is our object.
This study was conducted on IGF‑1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1st week
and 4–6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation.
IGF‑1 levels showed a
significant difference between neonates ≤1500 and 1500–2000 g (1 and 4–6 weeks,P = 0.008, P = 0.039, respectively). No significant
association was found between IGF‑1 and ROP.
Finding a meaningful association between IGF‑1 and ROP requires
consideration of factors affecting the IGF‑1.
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