Integrated Exercise and Glycemic and Peripheral Sensation Control in Diabetic Neuropathy: A Single‑Blind, Randomized Controlled Tria

Neuropathy control and management is an objective in therapeutic exercises prescribed for patients with Type 2 diabetic peripheral neuropathy. We examined the effects of 12‑week integrated exercise (IE) on glycemic control and peripheral sensation criteria in patients with diabetic neuropathy.

This study was carried out in 2019–2020 in Janan diabetic society of Najaf Abad in Iran. Based on MNSI scores, we assigned 40 patients into two equal paired random groups (control vs. IE). Pre and posttests were administered before and after three months of intervention.

Repeated measures ANOVA showed no significant interaction effect between the FBS of the groups (P = 0.26) but significant interaction effects were observed between the levels of 2 hrs pp G, 4 pm G, HbA1c, Diapason, Monofilament, and Thermofeel in favor of the IE group (P < 0.05).

At the beginning of IE, we used massage and foam roller to release pain and improve blood circulation as well as sensation in the neuropathic areas. This may have helped the patients perform the aerobic and resistance exercises more easily. Therefore, better glycemic control and peripheral sensation were achieved. Verification of the long‑term effects of this training strategy requires further study. Verification of the long‑term effects of this training strategy requires further study.