A case report of Posterior reversible encephalopathy syndrome with spinal cord involvement (PRES-SCI), an atypical presentation of PRES in children

Posterior reversible encephalopathy syndrome has a broad spectrum in clinical presentation and radiologic features. Diagnosis of posterior reversible encephalopathy syndrome (PRES) based on reversible clinical manifestations and sequential neuroimaging. Atypical MRI features were defined as hemorrhage, restricted diffusion or contrast enhancement of lesions, involvements of temporal and frontal lobes, brain stem, basal ganglia, corpus callosum, cerebellum, and spine. Atypical PRES with or without spinal cord involvement is a rare presentation, especially in children. Up to 2020, just 5 cases of posterior reversible encephalopathy syndrome with spinal cord involvement (PRES-SCI) have been published in pediatrics.