Targeted drug delivery by bone cements

Bone cement is one of the most crucial materials for the substitution of damaged bones. Polymer or ceramic can be used as cement materials. Systemic drug delivery to the bone is difficult since human bone lacks blood arteries. Bone cement can carry drugs directly to the bone without causing adverse effects on healthy tissues, so it is a good choice for targeted drug delivery. Growth factors and also anti-inflammatory, anticancer, analgesic, and antibiotic reagents are just a few of the medicinal chemicals that may be added into bone cement for various treatment tech-niques. Our goal in this review is to introduce diverse bone cements, drug loading mechanisms in bone cements, and ultimately their clinical applications in dental potentials, inflammation therapy, bone infection, treatment of osteoporosis, coating of implants, and cancer therapy.