Effects of Pomegranate on Wound Repair and Regeneration

Wounds may occur during both surgical and non-surgical procedures. The processes of repair and regeneration of injured tissues are important in wound healing.These processes involve an integrated action of cellular events beginning with inflammatory reactions, and then, the proliferation of the granulation tissue (mostly fibroblast cells), and angiogenesis. The final stage includes the remodeling of the collagen fibers which determines the tensile strength. Reduction of the recovery period may facilitate wound repairing and reduce complications such as infection and swelling. To date, many medications such as antibiotics, vitamins, and minerals have been introduced as wound healers. Despite these advances, more investigations are required to find new therapeutic medications for wound healing that have more healing effects, better clinical outcomes, and fewer side effects