Rescue potency of Eucalyptus oil against gamma-rays induced gastric ulceration
Eucalyptus oil often used for medicinal purposes.
The Eucalyptus oil gastro protective impact investigated against gamma-rays-exposure-induced gastric ulceration in rats. Materials and
Thirty-two rats were divided equally into 4groups; control, Eucalyptus oil (100mg/ kg), gamma-rays (7Gy) and Eucalyptus oil plus gamma-rays treated groups. The stomach histopathology samples were examined. The levels of malondialdehyde, reduced glutathione, superoxide dismutase, tumour necrosis factor-α and the interleukin-1β were assessed.
The stomach histopathological examination revealed that pre-treatment with Eucalyptus oil enhanced regeneration of mucosal crypt cells. The results revealed a decreased level of stomach malondialdehyde, inflammatory markers, increased levels of stomach antioxidants markers in Eucalyptus oil plus gamma-rays treated group.
Eucalyptus oil ameliorates gamma-rays-induced gastric ulceration that could attribute to its antioxidant, anti-apoptotic and radioprotective activities.
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