Association of CT Scan Parameters with the Risk of RenalAngiomyolipoma Rupture; a Brief Report

Rupture of renal angiomyolipoma (AML) is an emergency and life-threatening complication. Thisstudy aimed to evaluate the association of computed tomography (CT) scan parameters with the risk of rupturein renal AMLs.

In this retrospective cross-sectional study, patients who were referred to a referraluniversity hospital with diagnosis of AML, between 2007 and 2019, were included. Patients were divided intoruptured and non-ruptured cases based on surgery and CT scan findings and the baseline characteristics as wellas CT scan parameters were compared between the two groups.

20 AML patients with the mean ageof 39.6 ± 12.5 years were included (75% female). The lesion was ruptured in 8 (40%) patients. The mean sizeof the lesion was 97.0 ± 15.9 mm in the ruptured and 72.0 ± 29.4 in the non-ruptured AML (p = 0.045). Themean fat density based on non-contrast enhanced CT (NCCT) scan (-56.1 ± 16.3 vs -74.9±24.1; p = 0.018) andcontrast enhanced CT (CECT) scan (-20.8 ± 16.9 vs -50.5 ± 31.7; p = 0.016) was significantly higher in the rupturedcases. Total tumor density based on NCCT scan was significantly greater in the ruptured AMLs (19.6 ± 25.9 vs-22.7±41.6, p=0.033).

It seems that some CT scan parameters such as mean fat density and totaltumor density could be used for differentiation between ruptured and non-ruptured AMLs.