The effects of detraining following a regular exercise program on plasma resistin concentrations in asthmatic patients

The purpose of this study was to investigate the effects of regular exercise and the following detraining on plasma resistin concentration in patients with asthma. Climate change and reduced rainfall have caused allergies and respiratory diseases to develop in different people, resulting in 8.9% of adults suffering from asthma by 2025, and 400 million by 2050. Asthma prevalence or symptoms increase as a result of the secretion of some adipokines, such as the hormone resistin. Detraining results when there is insufficient training stimulus, causing the loss of training-induced adaptations. Training cessation or insufficient training can alter the detraining characteristics.

In the present study, 30 available asthmatics were randomly divided into control and exercise groups. For three months, the exercise group followed a regular training regimen that included three 90- minute sessions each week. Each training session included 60 to 85% of the patients' maximum heart rate on the treadmill or pedaling on an ergometer. The control group did not do any physical exercise in addition to their normal routines throughout the same time period. Blood samples were drawn before the first session, 2 days, and 1 month after the last sessions.

Serum resistin levels were not affected by the three-month regular training program or one-month detraining period. They did not differ significantly in the control group either (P >0.05).

Despite the benefits of regular exercise being beneficial for all individuals, asthma symptoms in asthmatics were relatively reduced, although these changes were not significant.