Effect of CPP‑ACPF, resin infiltration, and colloidal silica infiltration on surface microhardness of artificial white spot lesions in primary teeth: An in vitro study

Remineralizing agents such as fluoride and casein phosphopeptide‑amorphous calcium phosphate (CPP‑ACP) are popular treatment choices for incipient enamel lesions. Recently introduced resin infiltration enhances the esthetics of teeth affected by these enamel lesions. Furthermore, few studies reported the utilization of colloidal silica infiltration for the white spot lesions. However, the potency of these materials for treatment in primary teeth necessitates investigation. Thus, this study evaluated and compared the effectiveness of CPP‑ACP fluoride (CPP‑ACPF), resin infiltration, and colloidal silica infiltration on surface microhardness in artificial white spot lesions in primary incisors using the Vickers microhardness testing machine.

In this in vitro study, on the labial surface of 45 primary incisors, artificial white spot lesions were created by immersing them in a demineralizing solution. According to the evaluation method, random distribution of specimens into three groups: Group 1: CPP‑ACPF, Group 2: resin infiltration, and Group 3: colloidal silica infiltration. Specimens after treatment were stored in artificial saliva, followed by microhardness evaluation using Vickers microhardness. Microhardness readings at baseline, post demineralization, and after treating them with different materials were taken. The level of significance was 0.01.

Enamel specimens treated with resin infiltration showed a high microhardness mean value compared to CPP‑ACPF and colloidal silica infiltration.

Resin infiltration is a promising and effective treatment option for incipient enamel lesions followed by CPP‑ACPF compared to colloidal silica infiltration in primary teeth.