Effectiveness of 3D-printed models prepared from radiological data for anatomy education: A meta-analysis and trial sequential analysis of 22 randomized, controlled, crossover trials

Many academicians suggested the supplementary use of 3D‑printed models reconstructed from radiological images for optimal anatomy education. 3D‑printed model is newer technology available to us. The purpose of this systematic review was to capture the usefulness or effectiveness of this newer technology in anatomy education.

Twenty‑two studies met the inclusion and exclusion criteria for quantitative synthesis. The included studies were sub‑grouped according to the interventions and participants. No restrictions were applied based on geographical location, language and publication years. Randomized, controlled trial, cross‑sectional and cross‑over designs were included. The effect size of each intervention in both participants was computed as a standardized mean difference (SMD).

Twenty‑two randomized, controlled trials were included for quantitative estimation of effect size of knowledge acquisition as standardized mean difference in 1435 participants. The pooled effect size for 3D‑printed model was 0.77 (0.45–1.09, 95% CI, P < 0.0001) with 86% heterogeneity. The accuracy score was measured in only three studies and estimated effect size was 2.81 (1.08–4.54, 95% CI, P = 0.001) with 92% heterogeneity. The satisfaction score was examined by questionnaire in 6 studies. The estimated effect size was 2.00 (0.69–3.32, 95% CI, P= 0.003) with significant heterogeneity.

The participants exposed to the 3D‑printed model performed better than participants who used traditional methodologies. Thus, the 3D‑printed model is a potential tool for anatomy education.