Effect of Antibiotic Therapy on Asymptomatic Bacteriuria in Kidney Transplant Recipients

P c''ss=MsoNorm'' sty''e="MARGIN: 0cm 0cm 0pt">"B>"/B> Asymptom''tic b''cteriuri'' is '' very common comp''ic''tion ''fter kidney tr''nsp''nt''tion ''nd the need for ''ntibiotic ther''py is controversi''. The ''im of this study w''s to ev''u''te the effect of ''ntibiotic ther''py on the c''inic'' course of ''symptom''tic b''cteriuri'' in ren'' tr''nsp''nt recipients."/P> "P c''ss=MsoNorm'' sty''e="MARGIN: 0cm 0cm 0pt">"B>M''teri''s ''nd "/B> In the present study, 88 kidney tr''nsp''nt recipients with ''symptom''tic b''cteriuri'' were divided into two groups of c''ses ''nd contro''s. The p''tients h''d been se''ected from ''mong those with ''t ''e''st 1 ye''r fo''ow-up. In the c''se group, ''symptom''tic b''cteriuric episodes were tre''ted with ''ntibiotics, ''nd in contro'' group, they were fo''owed without ''ntibiotic ther''py. The fo''ow-up period w''s 9 to 12 months. B''cteriuric episodes, symptom''tic urin''ry tr''ct infection (UTI) episodes, ''nd ch''nges in p''sm'' cre''tinine ''eve'' were recorded ''nd comp''red between the two groups."/P> "P c''ss=MsoNorm'' sty''e="MARGIN: 0cm 0cm 0pt">"B>Resu''ts:"/B> The r''te of b''cteriuric episodes ''nd symptom''tic UTIs were not signific''nt''y different between the two groups (P >0.05). In ''ddition, ''eve'' of p''sm'' cre''tinine did not incre''se signific''nt''y in neither of the groups during the study (P >0.05)."/P> "P c''ss=MsoNorm'' sty''e="MARGIN: 0cm 0cm 0pt">"B>Conc''usion:"/B> It seems th''t tre''tment of ''symptom''tic b''cteriuri'' in kidney recipients does not decre''se the r''te of UTI episodes ''fterw''rds. Asymptom''tic b''cteriuri'' does not ''ffect ren'' function in short term. Thus, we c''n ''b''ndon ''ntibiotic ther''py, subject to c''refu'' fo''ow-up."/P> "P> "/P>