Efficacy of Three Commercially Available Fluoride Releasing Varnishes in Remineralization of Artificial White Spot Lesions Evaluated by Laser Fluorescence: An In Vitro Study

This study aimed to assess the remineralization of shallow and deep artificial white spot lesion (WSL) by the application of three fluoride releasing varnishes.

Sixty-four extracted premolars were subjected to acid attack inducing two depths of WSLs. Using a DIAGNOdent pen, teeth were divided into two groups according to the WSL depth: shallow enamel (SE) and deep enamel (DE). Then each was subdivided into four intervention groups of eight teeth each: MI varnish, Clinpro White varnish, Clinpro XT, or control (artificial saliva). Laser fluorescence were measured via DIAGNOdent pen at baseline, demineralization stage, 24 h, 4 weeks, and 8 weeks after intervention.

For each lesion depth, there were statistically significant differences among the agents after intervention (P < 0.01) and among time intervals for each group (P < 0.01).

MI varnish is more effective than Clinpro White varnish or Clinpro XT in remineralizing two depths of WSLs at different time points.