Investigating factors involved in oxidative stress from a genetic point of view in male infertility
Infertility is one of the problems that has various social consequences. The severity of infertility in different societies includes about 10 to 15% of couples, and approximately 45% of the causes of infertility in these couples are related to the male factor. Infertility has many causes, one of which is oxidative stress. Glutathione peroxidase is one of the moderators with selenium, and selenium can be placed in the form of selenocysteine in their structure. This enzyme is one of the most important antioxidant enzymes involved in the male reproductive system. It has been found that glutathione peroxidase levels decrease in infertile people. The purpose of this review study is to investigate the various causes of infertility in men, especially glutathione peroxidase 3 enzyme and its polymorphism in fertile and infertile men.
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