CT imaging findings and clinical correlation analysis of different clinical types of novel coronavirus pneumonia

To deepen the understanding of COVID-19 and provide a theoretical basis for clinical diagnosis and treatment, the clinical manifestations, laboratory test findings and chest computed tomography (CT) signs of this disease and the correlations among them were explored in this study.

A total of 85 patients with confirmed cases of COVID-19 were included, and their disease courses, symptoms and laboratory test results were recorded.

The main characteristics of COVID-19 infection were fever (56 cases), respiratory symptoms (47 cases), normal or decreased white blood cell count (84 cases), decreased lymphocyte count (43 cases), and increased C-reactive protein (CRP) level (37 cases). There was a positive correlation between fever and each of white blood cell count, lymphocyte count, and CRP level (P<0.05). Age, disease course, fever, lymphocyte count, CRP level and CT findings were statistically correlated. In the CT-positive group, the lesions were often multiple (57 cases) and peripherally distributed (53 cases). The main manifestations included ground-glass density shadows (61 cases), grid-like changes (47 cases), abnormal pleural changes (53 cases), abnormal blood vessels (52 cases) and bronchial abnormalities (40 cases).

Mild and common COVID-19 cases have certain characteristics, clinical manifestations and laboratory parameters are correlated with CT manifestations. The comprehensive diagnosis according to clinical manifestations, laboratory and CT characteristics can minimize the missed diagnosis rate.