Synthesis of Benzoxazole Derivatives Using Fe3O4@SiO2-SO3H Nanoparticles as a Useful and Reusable Heterogeneous Catalyst Without Using a Solvent

In the present study, a simple and rapid method using an effective heterogeneous nanomagnetic catalyst, Fe3O4@SiO2-SO3H, was used to prepare the 2-arylbenzoxazoles derivatives by a condensation reaction of aromatic aldehydes with 2-aminophenol without using solvent and at a temperature of 50 0C. This catalyst is magnetically recycled and reused several times without reducing its catalytic activity. It was demonstrated that Fe3O4@SiO2-SO3H is an economic catalyst that can be used several times without reducing the catalytic properties. Purifying of the final products was simple and easy, and the percentage of catalyst performance was satisfactory.