The effect of MCT1 polymorphism on muscle strength in male endurance, speed and strength athletes

The aim of the present study was to investigate the effect of MCT1 A1470T polymorphism (rs 1049434) on one repetition maximum muscle strength in young athletes of the speed and endurance strength group in the chest press and squat-smith tests.

49 young trained male athletes with average age (24.22±5.54 years), height (178.57±8.91 cm), and weight (75.32±13.31 kg) were included in this research with the entry criteria. Muscle strength was calculated during one session using a maximum repetition test in two parts of the upper body (chest press test) and lower body (squats) for each subject. ARMS-PCR method was used to determine the genotype of the samples.

The results showed that there is a significant difference between the genotypes of the MCT1 polymorphism in one repetition of the maximum muscle strength of the Scott-Smith test in athletes (F=51.3, p=0.038) that the TT genotype with the highest strength in the test Scott Smith was with him. LSD post hoc test showed that subjects with genotype (TT+AT) have more strength compared to subjects with genotype (AA+AT). In the strength group between genotypes (AA and TT) in one repetition of maximum Scott-Smith muscle strength, the difference It was significant (p=0.047, F=3.54) and people with TT genotype had the highest strength in the Scott-Smith test.

The TT genotype of the MCT1 polymorphism has been associated with the lower body muscle strength of athletes and the effect of this genotype was evident in the athletes of the strength group.