Effectiveness of cervical cerclage on pregnancy outcomes in pregnant women with the history of preterm labor

We aimed to investigate the effectiveness of Cerclage in the pregnancy outcome based on the obstetric history and find out how the timing of the cerclage insertion could improve the pregnancy outcomes.

We conducted a retrospective descriptive study that enrolled 210 women who underwent history-indicated Cerclage. In all the women, McDonald's method was performed. Demographic data and delivery history were retired from the informative hospital system (HIS). The pregnancies were divided into two groups, low-risk group defined as pregnant women with a history of preterm labor (PTL) or second-trimester loss (STL) ≤ 2, and a high-risk group referred to patients with a history of preterm labor or second-trimester loss (STL) ≥3, to compare the efficacy and timing of the Cerclage in both groups. The Pearson Chi-squared test, student t-test, and ANOVA test were performed by SPSS 26.0. p-value<0.05 was statistically significant

of 210 women enrolled in the study, 158 were low-risk. Our results show that the obstetric history and cerclage-related factors shortened the gestational age at cerclage insertion and delivery (p-value<0.05). Earlier cerclage insertion prevented preterm labor and improved neonatal outcomes. However, the time of cerclage insertion was later in the low-risk group, and the gestational age of the low-risk group was statistically significantly longer than the high-risk group (36.61±2 weeks in the low-risk group versus 35±2.14 weeks' gestation in the high-risk group) (p-value<0.001). Women in the high-risk group were significantly more likely to deliver a newborn with low birth weight or be admitted to the NICU ward.

Cerclage improved pregnancy and neonatal outcomes. The elective Cerclage was more effective in the low-risk group than the high-risk group.