Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study

One type of the developed COVID-19 vaccines that received emergency permission and was approved bythe food and drug administration (FDA) is the mRNA-based vaccine. The aim of this study is to gather information on theJordanian population’s experience with the vaccine’s side effects.

The study objectives were addressed througha cross-sectional study, which collected information regarding the short-term side effects experienced by the vaccinatedindividuals within one month following the injection of an mRNA-based COVID-19 vaccine. Data collection was carriedout in August 2021. Participants were invited to take part in a self-administered web-based survey created using GoogleForms.

Among the study’s participants (n= 533), about 56% experienced side effects after the first dose of themRNA-based COVID-19 vaccine. The most commonly reported side effects after the first dose were sore arm at theinjection site (91.6%), and fatigue (83.06%). The female gender was significantly associated with experiencing fatigue,discomfort, chills, and hair loss. Being over 30 years old was significantly associated with experiencing cough. Being asmoker was significantly associated with experiencing shortness of breath and gastrointestinal symptoms.

The mRNA-based COVID-19 vaccine side effects were common, yet, mild, local, and self-limited. The local pain at theinjection site was the most commonly reported side effect. Hopefully, the study’s findings will aid in lowering resistanceto vaccination.