Epidemiologic survey and clinic-pathologic assessment of endometrial cancer in Kermanshah during 2013-2018

Endometrial cancer is the most common gynecological cancer and accounts for six percent of malignancies in women. The aim of this study was evaluation of epidemiology of this cancer and clinico-pathologic characteristics of patients in west of Iran.

Forty four patients with endometrial malignancy referred to Imam Reza hospital in Kermanshah were included in this descriptive-cross sectional study. Data was extracted from archive files and pathology reports in the hospital.

The mean age of patients was 56.95+/_ 11.31 years and the majority were in the age range of 50-60 years. None of the patients had a history of tamoxifen therapy, oligomenorrhea, late menopause and premature menarche, infertility or alcohol use. The majority of patients had no family history of endometrial cancer (90.9%). A family history of endometrial adenocarcinoma was observed in only 4 patients. Endometrial adenocarcinoma (88.6%) and endometrial stromal sarcoma (11.4%) were the most common endometrial cancers in patients, respectively. Vaginal bleeding was reported as the most common clinical symptom in the majority of patients. The age distribution of patients showed that patients under the age of 60 years and also more than 60 years are mostly diagnosed with endometrial adenocarcinoma.

Endometrial adenocarcinoma is the most common endometrial malignancy in west of Iran, that mainly is presented in the sixth decade with vaginal bleeding. This cancer showed no obvious association with known risk factors in west of Iran.