EFFECT OF THE ONE PERIOD OF BOLDENONE, RESISTANCE EXERCISE, AND JUJUBE EXTRACT ON STRUCTURAL DAMAGE OF PANCREATIC TISSUE IN MALE WISTAR RATS

Today, the use of potent drugs is very common among athletes, and steroid hormones are being used to improve exercise performance. The aim of the present study was to investigate the side effects of anabolic Boldenone steroid on pancreatic tissue and the healing effect of jujube extract with resistance training on reducing these complications.

42 wistar male rats, aged 8-12 weeks, and weights 180-220 grams were studied. After two weeks of maintenance and getting used to the training protocols, the third week of exercise began. Subjects were randomly divided into 6 groups of 7 (Boldenone group and resistance training, Boldenone, Boldenone and Jujube extract, Boldenone without resistance training, Control and Sham) and were evaluated for desirable results.

The results showed that changes in weight gain in the hormone training group were significant (P=0), but in exercise groups alone (P=1.000) and hormone alone (P=0974) and jujube hormones (P> 0.05 - P =0989) has not been meaningful. High-dose steroids have been responsible for the destruction of pancreatic axins, islets of Langerhans and blood vessels.

The results showed that the use of high-dose anabolic steroids results in the destruction of pancreatic tissue and exercise and jujube extracts can be effective in reducing the destructive effects of steroids.