A case-control study to evaluate the levels of non-HDLCholesterol in lichen planus patients to rule out the risk of cardiovascular events

Multiple studies indicate the correlation between lichen planus (LP) and certain systemic disorders. Data suggest an increased incidence of dyslipidemia with LP. Abnormal lipid levels are major risk factors for developing atherosclerotic changes and cardiovascular disorders (CVD). Non-high-density lipoprotein cholesterol (non-HDL-C) is a reliable marker for cardiovascular events. If non-HDL-C levels are raised in LP patients, it would mean that these individuals are high-risk patients and should be investigated periodically. We aimed to find non-HDL-C serum levels in cases of lichen planus and compare them with controls. We compared lipid profiles between 100 cases of LP and 50 healthy controls. Non-HDL-C levels were significantly higher in cases than controls (P = 0.002). The non-HDL-C level was elevated in 67% of LP cases, compared to 42% of controls. We demonstrated higher levels of non-HDL-C in LP patients than in controls, confirming the increased risk of CVDs in LP patients.