Comparing of two different detection methods (HPLC and LC-MS/MS) for the determination and confirmation of ochratoxin A in liquorice extract powder

Article Type:
Research/Original Article (بدون رتبه معتبر)

Mycotoxins in food and feed are important risk factor for public health. There are many test methods for determination mycotoxins in food and feed and their products. The most common mycotoxins test method is based on high-performance liquid chromatography, but depend on the matrix, it is essential to develop validated methods of analysis and detection of them in food products. This study evaluated two different detection methods for the determination and confirmation of ochratoxin A (OTA) in liquorice extract powder. The detection of OTA was accomplished with high-performance liquid chromatography (HPLC) combined with fluorescence detector and Liquid Chromatography with tandem mass spectrometry (LC-MS/MS). The results indicate that the LC-MS/MS method was more specific and sensitive for the analysis and confirmation of OTA in liquorice extract than HPLC method because of false positive in HPLC method in some sample. So to comply with OTA legislation and consumer health protection, improvements in OTA analytical methodology is essential.

Advances in the Standards and Applied Sciences, Volume:1 Issue: 1, Autumn 2022
38 to 43  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!