Oxidative Decarboxylation of Arylacetic Acids: Novel Approach to the Synthesis of Aryl Aldehydes and Ketones

Oxidation and decarboxylation are among the most important processes in organicsynthesis. The combination of these two fundamental processes provides a novel syntheticstrategy, that is, oxidative decarboxylation. Over the past few years, considerable attentionhas been focused on such an attractive research arena. This review offers an overview of theutility of oxidative decarboxylation in the synthesis of various aryl aldehydes and ketonesfrom the corresponding arylacetic acids. The review is divided into three major sections. Thefirst section focuses exclusively on metal-catalyzed reactions. The second section will discussmetal-free approaches. The third will cover photoredox-catalyzed decarboxylative oxidations.Literature has been surveyed from the year 1980 to 2022