Evaluation of antibacterial activity of aqueous and ethanolic extracts of Dorema aucheri, Zataria multiflora Boiss and Ferulago angulata against certain pathogenic microbes

Due to the side effects of resulting from the consumption of chemical preservatives and also over increasing of bacterial resistance to the antibiotic, identification of natural origin antimicrobial compounds are very important. Therefore, the present study was performed to evaluate the antibacterial activity of aqueous and ethanolic extracts of Dorema aucheri, Zataria multiflora Boiss and Ferulago angulate.  The antimicrobial activity of extracts evaluated by Disc diffusion. The Minimum Inhibitory Concentrations (MIC) and Minimum Bactericidal Concentration (MBC) were determined by using the dilution method. The Z. multiflora Boiss extract had a strong antibacterial activity and stopped the growth of both Listeria monocytogenes and Staphylococcus  aureus in MIC  of  10 & 20 μg/ml in respectively. Also Dorema aucheri ethanolic extract had antimicrobial activity against Listeria monocytogenes at less concentration andalso it was effective on Escherichia coli in concentration of 40μg/ml. Moreover, Ferulago angulata ethanolic extract was effective on bacteria tested in concentration used. The highest diameter of inhibition zone was related to Dorema aucheri ethanolic extract on Listeria monocytogenes. According to the results, these extracts can be used as a potential sources of antibacterial compounds for food and pharmaceutical industries.