Determining the association between Congenital Heart Diseases in Fetuses with Plexus Choroid Cyst

This cross-sectional study aimed to investigate the association between congenital heart diseases (CHD) in fetuses with choroid plexus cysts (CPCs) detected through fetal anomaly sonography. The study was conducted at Masoumeh Children Hospital in 2019.

A total of 250 participants were enrolled using an available sampling method. Data collected included maternal age, gestational age, fetal sex, CPC presence, and CHD diagnosis. Fetal echocardiography was performed, and participants were categorized into groups with and without CHD. Statistical analyses were carried out using SPSS software version 22. Descriptive statistics, chi-square tests, and independent t-tests were employed for data description and comparison.

The mean age of mothers with CPCs was 32.1 ± 10.92 years, while in the healthy mothers' group, it was 32.78 ± 10.73. CPCs were observed in 57.8% of female neonates and 62.6% of male neonates, with no significant statistical relationship to fetal sex. Although the group with CPCs exhibited more abnormal fetal echocardiographic findings, no significant association was found between these findings and CPC presence. Additionally, no significant relationship was identified between pregnancy term and CPC presence.

Infants with Choroid Plexus Cyst had a higher incidence of congenital heart defects as seen on Echo, but there was no significant correlation between the presence of these cysts and heart defects. Thus, parents need not worry.