Assessment of the effectiveness of neoadjuvant chemotherapy for rectal cancer by MRI and PETCT: a meta-analysis

Author(s):
Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background

A meta-analysis of the effectiveness of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography Computed Tomography (PETCT) in assessing the effects of neoadjuvant chemotherapy (nCRT) for Rectal cancer (RC) was performed to provide a reference for better clinical assessment in the future.

Materials and Methods

Relevant literature on the assessment of the effects of MRI and PETCT on RC nCRT was screened through PubMed, Cochrane, EMBAS and other literature databases, and the final literature for analysis was determined after cross-screening by two study team members. Review Manager 5.3 software was used to assess the quality of the literature and extract relevant information such as authors, year of publication, and results, and meta-analysis was performed using Stata 15.1 software.

Results

Through screening, six references were finally included, totaling 396 cases of study subjects, and the results of literature quality evaluation showed that the selected literature was of high quality and had some reference value. Meta-analysis revealed a sensitivity of 0.76 and a specificity of 0.74 for the final combination of MRI; the sensitivity and specificity of the final combined PETCT were 0.78 and 0.71, respectively.  Deek’s test showed P>0.05 for both MRI and PETCT, with no publication bias.

Conclusion

MRI and PETCT are similarly effective in predicting the effect of RC nCRT.

Language:
English
Published:
International Journal of Radiation Research, Volume:22 Issue: 1, Jan 2024
Pages:
85 to 90
magiran.com/p2708888  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!