Volumetric and Viscometric Studies of Nucleosides, Nucleotides and Furanose Sugar in Aqueous Medium from 288.15 to 298. 15K

Density (/g cm-3) and viscosity (/10-2gcm-1s-1=1centipoise,CP) of guanosine monophosphate (GMP) and adenosine triphosphate (ATP) referred to as nucleotide, and 2-deoxy adenosine (DOA) and thymidine (TMD) as nucleoside along with their integral furanose sugar, 2-deoxy ribose (DOR) from 0.0004 to 0.0014mol kg-1 solution have been measured at 288.15, 293.15 and 298.15K at atmospheric pressure. The  was fitted into the Masson and  in Jones-Dole equations for apparent molal volume (V /cm3mol -1) and viscosity coefficient ((r-1)/m=B/kg mol -1=10 3gmol -1) data. The V and  were also regressed for V 0 and 0 values known as the limiting constants and illustrate solute-solvent and solute-solute interactions of systems. The apparent molal volume of their various integral units like adenine, guanine and thymine of nucleotides and nucleosides are estimated by V 0 The V 0 0 and B values have been used to elucidate the hydrophilic and hydrophobic interactions. The V 0 values are negative over the whole range of the compositions which infer greater intermolecular forces and the biomolecules as water structure breakers