The effect of a single exhaustive endurance exercise session on the lipid peroxidation and serum total antioxidant capacity in wistar rats

Production of the reactive oxidative species (ROS) as free radicals resaults in oxidative stress and therefore cell structural damage following the exercise. This study aimed to investigate the effect of a single endurance exercise session on the lipid peroxidation biomarker, malondealdehyde (MDA) and serum total antioxidant capacity (TAC) in wistar rats. Thus 14 wistar rats aged 4 month were assigned randomly into one of 2 groups: rest (n=7), and endurance exercise (n=7). All groups were subjected a familiarization treadmill protocol for two weeks that started with walking and progress to the running speed 10 m/min. Finally, rats in endurance exercise group exercised at 70%vo2max. The running speed were 25 m/min at a gradient 5% in endurance group. Blood samples taken following the exercise from rested and exercised groups.  Serum total antioxidant capacity (TAC) and serum malondealdehyde (MDA), were measured. Results showed: The MDA increased significantly following endurance exercise in the endurance group compare to the rest group (p</01). The TAC increased significantly following endurance exercise in the endurance group compare to the rest group (p</05).