Percutaneous bone marrow grafting of fracture (An experimental study in rabbits)

Since bone marrow has been shown to contain osteoprogenitor cells, an experiment was devised to test its effects when injected percutaneously into osteotomies sites in rabbit radii. In this experimental study, the osteogenicity and its effect on early bone repair of bone marrow grafts were investigated. The purpose of this study was to determine whether bone marrow grafted percutaneously led to increased bone production or had any effect on the early healing of fractures. The parameters tested included, cross-sectional area of callus (XS), breaking load (BL), tensile strength (TS) and callus volume (CV) at the fracture site. At two weeks post grafting four parameters, specially callus volume, were significantly higher 0.001