Diffuse Bilateral Breast Uptake on the Myocardial Perfusion SPECT of a Nursing Female

Bilateral diffuse intense breast uptake was noted in a 40 year old female who was evaluated with Tc-99m sestamibi (MIBI) myocardial perfusion scan for possible ischemia. She was breast feeding her 1.5 year old child. The intense uptake in the breasts was superimposed on the apical and anteroapical regions of the myocardium and caused interpretation problem. We recommend considering Tc-99m MIBI breast uptake during breast feeding as a possible cause of non-interpretable, superimposition of radiotracer on the myocardium in myocardial perfusion scan.