FREQUENCY OF H.PILORI INFECTION AND GASTRIC AND DUODENAL LESIONS IN PATIENTS

The role of helicobacter pylori infection in gastric and duodenal lesions(benign and malignant) is well known. In this study 170 patients who referred to internal medicine clinic in Firoozabadi hospital and complained from dyspepsia were accepted. One group was older than 45 years with dyspepsia and the other group was younger than 45 years with dyspepsia whose symptoms had not been treated after 2 weeks of treatment. The aim of this study was to determine the frequency of H.pylori infection and its relation to duodenal and gastric lesions. 91 patients (53.5%) were female and 79 patients (46.5%) were male. 50% of patients were illiterate and only 2.9% of our cases have education higher than diploma. The reports of pathology were classified in 11 groups that 29.4% of cases suffered from chronic gastritis with lymphoid follicle in lamina proproa in association with H.pylori. Two cases of adenocarcinoma in stomach were reported. 50% of cases suffered from dyspepsia over 1 year without any assessment to detect H.pylori infection. In conclusion, the rapid diagnosis of peptic lesions due to H.pylori is very important because the chance of stomach cancer will decrease after treatment.