Palmoplantar Psoriasis: Calcipotriol and Local UVA Radiation

Palmoplantar psoriasis could hardly be differentiated from chronictylotic eczema both clinically and histologically. The most commonly used therapeuticoptions for palmoplantar psoriasis are long-term therapy with topical corticosteroidsand local PUVA. Frequently, it is a recalcitrant disease. We investigated the efficacyand tolerability of the combination of topical calcipotriol with local UVA radiationin comparison with local PUVA therapy. In a total of 43 patients with palmoplantar psoriasis, 33 were given 15sessions of local UVA radiation and topical calcipotriol and the remainder received15 sessions of local PUVA (psoralen + UVA radiation). The statistical analyses of the results showed that the effect and tolerability of both therapeutic modalities are comparable. Combination of topical calcipotriol and local UVA radiation is anoptional corticosteroid-free therapeutic modality for palmoplantar psoriasis. It hasa comparable effectiveness and tolerability with local PUVA.