فصلنامه طب و تزکیه
سال بیست و پنجم شماره 4 (پیاپی 101، زمستان 1395)

Colorectal cancer (CRC) is one of the most common types of cancer affecting 1.23million individuals per and is the third most common cancer in males and the second in Females. In addition¡ it is the third most common cause of cancer-related death.In recent years Oxidative stress and Chronic inflammation are believed to be two of the risk factors of colorectal carcinogenesis that have an important role in colorectal cancer(CRC). Biological and epidemiological studies indicated that some factores such as diet an life style can prevent incidence of CRC.Conjugated linoleic acid (CLA) is one of the functional lipids and is known to have physiological benefits such as the prevention and attenuation of lifestyle-related Colorectal cancer.
PubMed¡ Google scholar¡ ISI webofknowledge and Scopus were searched for studies published between 2000 till 2015. “inflammatory”¡ “anti oxidant”¡ “Rat”¡ “Conjugated linoleic acid” in combination with “Colorectal”¡ “Cancer” were used as search terms. Clinical trials with high quality and review articles were collected.
it is suggested reduction of inflammatory factors level as a key point in controlling cancer is a novel approach to prevent malignancy. For this purpose dietary CLA is suggested as a powerful factor to decrease inflammatory factors and increase anti oxidant factors level.

Colorectal cancer is the third cause of cancer death in the world and also in Iran. Recent studies in Iran show that colorectal cancer incidence has increased dramatically in the three recent decades. The current review was conducted to investigate the effect of dietary conjugated linoleic acid and serum Visfatin levels on the risk of developing colorectal cancer.
PubMed, Google scholar, ISIwebofknowledge and Scopus were searched for studies published between 2000 till 2015. “NAMPT”, “Visfatin”, “PBEF”, “Rat”, “Conjugated linoleic acid” in combination with “Colorectal”, “Cancer”, “Neoplasm” and “malignant” were used as search terms. Clinical trials with high quality and review articles were collected.
Various studies show that conjugated linoleic acid (CLA) prevents metastasis and progressive cancers especially colorectal cancer by different ways such as inducing apoptosis and aggregating of tumor suppressor proteins. It has been concluded that the serum Visfatin levels increase in different cancers and a positive correlation between serum Visfatin levels and metastasis has been shown.
It is suggested that reduction of serum Visfatin level as a key point in controlling cancer is a novel approach to prevent malignancy. For this purpose dietary CLA is suggested as a powerful factor to decrease serum Visfatin.

factors associated with quality of life in cancer patients and their spiritual needs an important role in evaluating the effectiveness of treatment and the disease process so that in recent years to identify and meet the spiritual needs of cancer patients as a desirable goal and Nursing care is an important safety consideration. This study aimed to determine the relationship between quality of life and spiritual needs of patients in oncology hospitals in Kerman University of Medical Sciences in 2015.
This descriptive correlational study, 150 patients with cancer were selected based on sampling. Collection tool questionnaire data quality of life of patients with cancer (QLQ-C30), a questionnaire was spiritual needs. Data using descriptive test, Spearman, Mann-Whitney and Kruskal_Varlys and Whitney using SPSS software version 19 was analyzed at the significant level of 0.05.
The results showed that there is a need for spiritual and quality of life (p-value= 0.0001) this indicates is that the spiritual needs include the need for meaning and purpose in life, the need to receive love and affection, the need for hope and creativity, the need for forgiveness, honest relationships with self, others and God by improving the quality of life there.
the role of quality of life and spiritual needs of patients with cancer can cause patients cope with the disease and improve the treatment of these patients.

With increasing rate of urbanization in the globe, the problem of marginalization and health status of marginalized group, although with a different severity has been turned to a big issue for all nations and countries, in a way that slums have been addressed directly in the 11.1 of Sustainable Development Goals. The United Nations Human Settlements Programme estimates that 863 million people living in slum areas (2014), According to the 2015 census of Ministry of Health and Medical Education in Iran 10,280,270 people lived in slum areas (2015) and again according to this census this rate for Tabriz University of Medical Sciences is about 505,356 persons. This article as an independent assessment intends to introduce and discuss the Tabriz experience in this regard in line with universal health coverage for marginalized groups.
This paper has been conducted through qualitative methods, interviews, documents reviewing, data comparison before and after the implementation of health transformation plan and field surveys by two separate teams (national and provincial).
By implementing the health complex strategy in marginalized areas the number of health institutions and healthcare workers has been significantly increased in these areas (a health team for 4000 persons and a 62000 population for a health complex, Diabetes cases detection has been increased from 30 to 621 and detection of heart diseases increased from 5 to 167, Meanwhile essential packages and supportive services provided to the population by governmental subsidy , as well as managerial practices and payment methods were used much more efficiently than in the past.
The implemented structures used to the health transformation plan were varied in different provinces. Recognizing the strengths of different structures and introduce them¡ will provide a structural design based on the experiences of all provinces.

Road traffic accidents accidents in Iran due to high frequency of their victims are the second cause of mortality. Considering the burden of road traffic accidents, it is necessary to provide a proper information setting for decision makers with analysis of current data in order to prevent and control road traffic accidents. Esfahan province is considered as one of the main roads with high traffic because of its touristic attractions and also its location in the in the country main traffic roads. Esfehan has 10 percent share of total transportation in country with daily transferring of more than 40 million ton cargo and 30 thousand passengers. Therefore, Esfahan province is considered as one of the high traffic ways in which the road accidents occur increasingly. This research is accomplished to investigate the epidemiology of fatal driving accidents in Esfahan province in 2012. In this cross-sectional study, all data of deaths following Isfahan traffic accident injuries in 2012 reported by forensic medicine organization were used. All received information first were controlled and then using Stata 11 were analyzed in terms of epidemiological variables. Relations of some effective variables on accident were also evaluated by statistical tests. Raw andage standardized incidence were 24.4 and 24.3 in 100000 person, respectively. Most of the studied subjects were male (79.98%) and between the ages of 15-44. suburbanaccident rate was also calculated based on the total number of vehicle transits in suburban roads that most of them happened in 6:00 AM and September.accoring to the location of accident 50.38% of them occurred in suburban roads. Cause of death in most of the accidents head injury (48.02). there was statistically Significant relation between crash site, vehicle type and the way of accident occurrence.
The study results indicate that accidents resulting in death most occurred in low educated males, between the ages of 15-44years and in July and September. Since more than 40 % of deaths was due to head injury, preventive measures and proper planning is necessary to decrease the deaths caused by accidents and increase the road safety especially in suburban roads.

The aim of this study was to investigate the relationship between social support and marital adjustment and mental health of married women working in a governmental organization.
This study is descriptive-analytic and applied was conducted in 2016 were selected as examples. Standard information gathering questionnaires assessing social support Sherborne and Stewart, Dyadic Adjustment Scale Spanier and General Health Questionnaire Goldberg. For analysis data from one sample t test, Pearson correlation and regression was used to test the hypothesis.
The results showed that about 65 percent of participants scored above the cut-off point in the General Health Questionnaire. Results show that the mental health of women working in a governmental organization has been unfavorable. It was also found to improve social support and marital adjustment, mental health of women working proliferate for about 70 percent of mental health changes to components of social support and marital adjustment is predictable.
Due to the influence of social support and marital adjustment on the mental health of working women. Providing training and adequate consultation and Mstmrbh couples before and after marriage. And focusing on the promotion of social support with the aim of improving the quality and quantity of supportive networks there can strengthen the protective effect.