مجله دانشگاه علوم پزشکی ایلام
سال بیست و هشتم شماره 2 (پیاپی 121، خرداد 1399)

It is highly crucial to develop novel strategies in order to further enhance the monitoring of sudden cardiac arrest in athletes and establish standard medical care procedures to control monitoring and treatment costs. Therefore, this study aimed to investigate the effects of a high-intensity competition on cardiac troponin T (cTnT) and its correlation with the corrected QT interval (QTc) in the trained athletes.

In total, 32 male athletes (mean age: 26.9±4.7 years, body mass index: 25.6±1.6 kg/m2) competed in 8-min high intensity competitions. The competition items included running on skillmill for 400 meters; three-stage deadlifting, weight lifting (110kg) with 5 repetitions; (130kg) with 3 repetitions; and (150kg) with 1 repetition, bar pulling up with 30 repetition, 30-kg kettlebell swinging, and 20 sandbag throwing with different weights at a distance of 5m behind a 75-cm box. Moreover, lead II electrocardiogram was utilized in order to measure the resting QTc. The intravenous blood test was performed to determine the level of troponin T before and immediately after the competition. In addition, ANOVA with repeated measures was used to examine the differences between variables in resting position, post competition, and after correction for the volume of plasma lost. In addition, Bonferroni post hoc test was used to identify which mean differences were statistically significant. The Pearson Correlation Coefficient was calculated to assess the level of correlations between the variables and QTc. Ethics code: IR.SRTTU.SSF.2018.103

The results showed an immediate significant increase in the cardiac Troponin T after high-intensity competition, compared to the resting position (P<0.001). However, when raw post-exercise data were corrected for plasma volume loss, no significant difference was observed in this regard (F1,31= 832, P<0.001). Furthermore, the Pearson results indicated that there was no significant correlation between the resting QTc and cTnT before and after the high-intensity comoetition.

There was no significant correlation between the QTc and cTnT among the trained atheletes after high-intensity competition. The QTc can not probably be ragrded as an independent high-risk predictor for myocardial damage and cTnT release in athletes. However, there is a need for more studies on athletes in different sports.

The cause of preeclampsia has not been identified so far; therefore, it accounts for a high percentages of maternal hospitalization. It seems that polymorphisms of genes encoding antioxidant system enzymes are effective in the pathophysiology of this disorder. This study aimed to evaluate the relationship between CAT-262 C/T polymorphism of enzymatic antioxidant Catalase gene and preeclampsia.

This case-control study was conducted at Islamic Azad University of Kazerun, Kazerun, Iran, in 2017. In total, 150 preeclampsia patients and 150 healthy pregnant women were selected as cases and controls, respectviely.  After DNA sampling and extraction, the CAT-262 C/T polymorphism was determined by Polymerase Chain Reaction and Restriction Fragment Length Polymorphism method. Data were analyzed in SPSS software using the Chi-square and Yates corrected X 2 statistical tests. Ethics code: IR.IAU.KAU.REC.1398.005

Results showed a significant difference between preeclampsia patinets and healthy preganat women regarding the frequency of CC, CT, and TT genotypes (PCAT=0.32) and both C and T alleles (PCAT=0.42) in the position of the CAT-262 C/T polymorphism of enzymatic antioxidant Catalase gene. Except for the multiple pregnancy parameter (PCAT=0.007), no significant diffrences were observed between the case and control groups in terms of other measured factors, such as the severity of preeclampsia (PCAT=0.272), urinary protein excretion (PCAT=0.130), patient swelling (PCAT=0.739), age at onset of disease (PCAT=0.412), primipara (PCAT=0.322), multipara (PCAT=0.074), previous history of preeclampsia (PCAT=0.630), history of miscarriage (PCAT=0.287), diabetes mellitus (PCAT=0.75), and hypothyroidism (PCAT=0.941).

According to the results of this study, the CAT-262C/T polymorphism could be considered as a risk factor for preeclampsia susceptibility in the south of Iran.

The combined therapy of cancer is more effective than using a single medication for the treatment of cancer. This study aimed at investigating the anticancer effects of cisplatin and cisplatin in combination with Titanium dioxide (TiO2) nanoparticles on the PC-3 prostate cancer cells.

The PC-3 cells were cultured in a RPMI1640 medium. Cell viability was assessed by MTT assay during 24, 48, and 72 h, and IC50 was determined. The RNA was extracted, and then the cDNA was synthesized. The expression level of BCL2L12 gene was compared to that of the TBP reference gene using Real-Time Polymerase Chain Reaction method.

Cisplatin and cisplatin with TiO2 nanoparticles exerted a dose and time dependent inhibitory effect on the viability of PC-3 cells. The expressions of the BCL2L12 gene in cisplatin-treated PC-3 cells at 24, 48, and 72 h were 3.58, 0.08, and 0.17, respectively. Moreover, the corresponding values in cisplatin-treated cells with TiO2 nanoparticles (10μg/ml) were 0.09, 0.05, and 0.02 at 24, 48, and 72 h, respectively, and in cisplatin-treated cells with TiO2 nanoparticles (25μg/ml) were 0.54, 0.04, and 0.07 at 24, 48, and 72 h, respectively (P<0.05).

This study revealed that simultaneous treatment with cisplatin and TiO2 nanoparticles (10μg/ml) at low concentration (6.2 and 12.5) can cause more cell death than cisplatin treatment alone. This may be due to the facilitation of cisplatin entry into the cell in the presence of TiO2 nanoparticles.

Occupational stress is recognized as one of the most serious occupational hazards in developed countries. Stress-related problems can cause behavioral, mental, and physical symptoms leading to a decrease in work performance. This study aimed to investigate the effect of aromatherapy using lavender extract on staff job stress in the operating room environment.

This quasi-experimental study was performed on 25 staff in Hojat ibn-al-Hassan al-Askari Hospital in Isfahan during September 2017. The study sample was selected using the convenience method. Data were collected using a researcher-made questionnaire with confirmed validity and reliability. The operating room staff were asked to complete the questionnaires before and after aromatherapy. The data were analyzed using descriptive and analytical statistical tests (mean and Wilcoxon test).

The results of the study showed that aromatherapy had only a significant effect on one of the symptoms of job stress (i.e., feeling calm at the workplace). However, there was no statistically significant difference before and after the intervention regarding the total occupational stress of the staff.

Due to the effect of aromatherapy with lavender extract on some symptoms of occupational stress, this method can be used in the operating room environment to reduce occupational stress among staff.

Esters of phthalates, particularly di-(2-ethylhexyl)-phthalate (DEHP) generally utilized in plastic industry are environmental hazardous pollutants, has toxic effects on body systems, including reproductive system. The aim of this study was to evaluate the effects of Achillea millefolium on rats’ sperm exposed to DEHP.

In this study, 45 male rats were randomly divided into 9 groups. 1- Control, 2- sham, received corn oil, 3- received 75mg/kg/day hydro alcoholic extract of Achillea millefolium inflorescence, 4- Low-dose diethyl-hexyl–phthalate (DEHP1), 5- Low-dose diethyl-hexyl–phthalate+Achillea millefolium, (DEHP1+A) 6- Medium-dose diethyl-hexyl–phthalate (DEHP2), 7- Medium-dose diethyl-hexyl–phthalate + Achillea millefolium, (DEHP2+A) 8- High-dose diethyl-hexyl–phthalate (DEHP3), 9- High-dose diethyl-hexyl–phthalate + Achillea millefolium (DEHP3+A). All of groups except the control group were treated by gavage for 40 days. After euthanized, the epididymal sperms are collected to investigate the sperm parameters. Data were analyzed using ANOVA and Tukey post hoc tests.

di-(2-ethylhexyl)-phthalate significantly (P<0.05) decreased the sperm parameters including, count, viability, motility and maturation of the nucleus and significantly increased the breakage of sperm nuclear DNA in comparison to control group. Achillea millefolium inflorescence hydro alcoholic extract had a positive effect on these parameters.

More likely Achillea millefolium inflorescence hydro alcoholic extract has antioxidant effects thus reduces the injurious effects of di-ethylhexyl phthalate on sperm parameters.

Employee adherence to professional principles and behavior can have a significant impact in terms of enhancing employee productivity and changing the attitude of customers towards the organization. On the other hand, ethical behavior along with the responsibility of nurses and patient care personnel has an important role in improving and restoring their health and can increase their commitment to the organization. Organizational commitment is one of the most important concepts of any organization in any size and part. The success of the organization is the result of the commitment of the staff of the organization. In fact, it can be said that organizational commitment is one of the most important characteristics of organizations that makes them different.This study aimed at investigating the Effect of Spiritual Intelligence on Organizational Commitment according to Professional Ethics mediator in Ilam Health Center.

This practical study was conducted based on a descriptive design. The study population included Ilam Province Social Security Staff. The samples were selected using the Morgan table through a simple random sampling method. The data were collected using a questionnaire, and they were analyzed in SPSS software (version 21).

Effect of Spiritual Intelligence (P<0.50, β=0.179) was investigated on Organizational Commitment according to Professional Ethics mediator (P<0.50, β=0.346) in a Health Center in Ilam, Iran. Spiritual intelligence (P<0.50, β=0.520) had a significant impact on organizational commitment. The findings showed that higher spiritual intelligence among the employees led to higher levels of professional ethics, and therefore, their greater organizational commitment.

According to the results, higher capacity of spiritual intelligence in the organization results in greater level of organizational commitment. Moreover, higher levels of professional ethics in the organization leads to greater organizational commitment. It can be concluded that spiritual intelligence has a significant effect on professional ethics. In other words, regarding spiritual intelligence, professional ethics makes progress or regress. Given the positive relationship between spiritual intelligence and professional ethics and also the organizational commitment, it can be concluded that the health center should take steps towards making the employers more committed using the strategic education programs that include the essential principles of spiritual intelligence and professional ethics.

The timely diagnosis and prediction of diseases are among the main issues in medical sciences. The use of decision-making systems to discover the underlying knowledge in the disease information package and patient records is one of the most effective ways of diagnosing and preventing disease. This study aimed to design a medical decision system that can detect hepatitis.

This study was conducted based on a descriptive-analytic design. Its dataset contains 155 records with 19 features in the University of California-Irvine machine learning database. This study utilized the Binary Artificial Algae Algorithm (BAAA) for Feature Selection (FS). Moreover, K-Nearest Neighbor (KNN) was used to classify hepatitis into two healthy and unhealthy classes. In total, 80% of the data was employed for training, and the remaining (20%) was used for testing. Furthermore, Precision, Recall, F-measure, and Accuracy were utilized to evaluate the model.

According to the results, the accuracy of the proposed model was estimated at 96.45%. After selecting the features with the BAAA, the percentage of the accuracy reached 98.36% in the best situation. In the proposed model with 300 repetitions, the Precision, Recall, F-Measure, and error rate were 96.23%, 96.74%, 96.48%, and 3.55%, respectively.

Hepatitis is one of the most common diseases among females and males. A timely diagnosis of this disease not only reduces the costs but also increases the chance of successful treatment. In this study, the disease was diagnosed using the hybrid method, and a high accuracy level was obtained in disease diagnosis by FS.

Little is known about the pathogenicity and virulence properties of the Rhizopus species used in food fermentation. This study aimed to investigate the virulence potential of Rhizopus arrhizus and R. microsporus strains obtained from a wide selection of clinical and environmental sources in an embryonated chicken egg model.

In total, 26 strains (13 strains from each species) were inoculated in embryonated eggs with final concentration of 106 spore/ml/egg. The eggs were inoculated (0.1 ml) through chorio-allantoic membrane in day 10 and incubated at 37.6 °C and 60% humidity and monitored for 7 days. Ethics code: IR.MUMS.fm.REC.1396.457

The mortality rate for R. microsporus was slightly higher than that of R. arrhizus. The ability of R. arrhizus and R. microsporus to cause infection was strain-specific but source-independent in the embryonated chicken eggs. The presence of endosymbiont bacteria (Burkhulderia) in some strains of R. microspores did not show any effect on their virulence.

The occurrence of virulence in strains isolated from fermented food indicates the opportunistic nature of these fungi and possibility of a public health risk for consumers.

Any kind of behavior or practice that conflicts with the values ​​and norms accepted by the community is known as social harm, which can disrupt the function of the individual, the family, and the community. This study aimed to investigate the factors leading to social injuries among dormitory students.

This descriptive-analytic study was carried out on 337 dormitory students of the state universities in Ilam during 2016. The data were collected using a researcher-made questionnaire with 69 items.  Face validity, relative content validity coefficient (CVR), and content validity index (CVI) were used to evaluate the validity of the instrument. In this study, the CVI and CVR were obtained at 0.85 and 0.76, respectively. The reliability of the questionnaire was assessed by Cronbach's alpha coefficient at 0.87. Data were analyzed in SPSS software (version 20) through descriptive statistics to describe the data. Moreover, inferential statistics were used to analyze the data.

The Chi-square test results showed a significant difference between gender and the damage induced by the illegitimate relationship (P<0.05). Moreover, social injuries correlated significantly with friend status, being isolated, lack of familiarity with life skills, and lack of academic and educational facilities in dormitories (P<0.05).

In this study, family problems, history of depression, presence of peer group and friends, and being far away from family were the most important factors affecting social harm in students. Therefore, it is suggested to develop appropriate strategies to prevent the emergence of social harms.

Surgery is a very stressful situation for patients. In addition to physical variables, psychological components also affect the patients who are ready for surgery. This study aimed to investigate the relationship of psychological factors with immunological and physiological factors regarding the moderating role of personality trait D in patients ready for surgery at Imam Khomeini Hospital, Ilam, Iran.

The present study was conducted based on an analytical and correlational design. The population of this study included the patients who were ready to undergo surgery at Imam Khomeini Hospital, Ilam, Iran. In total, 60 people (30 females and 30 males) were selected using the available sampling method. The data were collected using Perceived stress questionnaire, Spielberger anxiety questionnaire, personality type D questionnaire (DS-14), and blood samples of the patients to measure the blood factors. The data were analyzed in SPSS software (version 21) using descriptive and inferential statistics.

The results showed a significant relationship of psychological variables (stress, anxiety, personality trait D) with immunological (cortisol) and physiological (blood factors) variables (P<0.01). The results of regression analysis also showed that psychological variables (stress and anxiety) are able to predict the immunological and physiological states of the patients who are ready for surgery. It is worth mentioning that personality trait D also plays a significant role in this regard.

The results showed that the immune disorders during surgery created by psychological variables can cause biological changes in terms of health risk. Given the effect of psychological variables on the immune system, it is recommended to evaluate people with personality type D since this personality type can have effects on blood factors before and after surgery which can be an appropriate guideline for psychological interventions.