International Journal of Hospital Research
Volume:9 Issue: 1, Winter 2020

Tramadol overdose is inappropriately prevalent in Iran and is one of the most common causes of hospital admissions in recent years. Tramadol is both a codeine family and a weak opioid receptor agonist (AG) that is used at regular doses as an analgesic and may lead to seizures. The aim of this study was to investigate the relationship between physiological effects of high dose tramadol administration and cytochrome c enzyme gene polymorphism. CYP2D6) p450) in patients with tramadol intoxication referring to the poisoning ward of Razi Hospital, Ghaemshahr city,Mazandaran province was surveyed. This cross-sectional study was performed on 121 patients admitted for poisoning ward of Tramadol only in 2016. Also, these patients do not have any previous underlying diseases such as cardiac and renal complications, etc. 60 of the patients had seizure due to tramadol. At first, demographic characteristics of patients and factors evaluated were extracted in a questionnaire and ml of each patient. 5th was taken blood. After preparing the samples, RFLP - PCR was used to evaluate the CYP2D6 gene polymorphism (rs1065852). The mean age of patients was 25 years. 78% of them were smokers. Statistical methods were considered as p

Use of information technology in Pharmaceutical supply chain management provides improved visibility and accountability.The aim of this study is evaluating the approaches of using IT in the pharmaceutical Supply Chain Management by Decision-Making Trial and Evaluation.

In this mixed study, the Information Technology experts and executives were included in the FDA,the MOHME in a way that10of them would complete the paired comparison questionnaire purposefully.four main criteria of Information Technology were identified and30features were categorized as sub-criteria.The selected factors were considered as the effective factors of using the Information Technology in fewer than four strategies in the pharmaceutical supply chain.Finally,the effectiveness of any strategy was determined according to criteria using the Decision-Making Trial and Evaluation.

According to the obtained results during the trial and evaluation,the mechanism criteria had the most effect and structure was found to have the greatest influence on other criteria among the four determined criteria.

the strategy to achieve agility in the pharmaceutical supply chain has received the most effect and assessing the pharmaceutical supply chain was found to have the greatest influence on other criteria.Since there are many effective factors in choosing the right strategy for using the Information Technology systems,determining the influence value of each factor can be a sensitive step for the decision-makers.Also,it can add to the favourable effect of the pharmaceutical supply chain.

The purpose of this study was to compare metacognitive therapy compared to positive therapy on symptoms of depression and psychological well-being.  

The female patients with confirmed coronary artery disease and Addmited to the CCU ward in the first half of 2019 were included in the study. Patients were selected using the available sampling method in 3 groups of 15 subjects and answered Beck's depression questionnaires (1972) and Reef's psychological well-being (1980) before and after the intervention of metacognitive therapy or positive therapy, while the control group didn't receive any therapies. Multivariate and variable covariance analysis was used to analyze the data using SPSS 21 statistical software.

The results of data analysis showed that metacognitive and positive therapies are effective in treating the symptoms of depression and psychological well-being. There is a difference between metacognitive therapy and positive therapy on the symptoms of psychological well-being. Metacognitive therapy has a greater effect on the symptoms of depression and psychological well-being in women with coronary artery disease (p <0.01).

Therefore, it is concluded that metacognitive therapy has a great capacity to create and empower the mental health of patients with coronary diseases, which requires more attention in further researches.

Background and Objective :

this study was evaluation of satisfaction, burnout, compassion, and secondary traumatic stress and related factors among residents working in training hospitals.

This descriptive-analytical, cross-sectional study was performed on medical residents working in Imam Khomeini Training Hospital in Sari, Iran, affiliated to Mazandaran University of Medical Sciences, in 2019. Data were collected using a demographic characteristics questionnaire and the professional quality of life scale (ProQOL). Data analysis was performed in SPSS version 24.

Among 300 subjects evaluated, 134 were male (44.7%) and 166 were female (55.3%). In addition, the mean age of the residents was 29.24±3.42 years. According to the results, the mean and standard deviation of satisfaction with compassion, occupational burnout, secondary stress at workplace and compassion fatigue were estimated at 21.99±8.22, 38.46±4.17, 28.30±4.58, and 33.38±3.19, respectively. There was a significant relationship only between satisfaction with compassion and gender (P<0.001). Significant relationship was observed between the dimensions of satisfaction with compassion and job burnout (P<0.001).

According to the results of the study, female residents had a higher level of satisfaction with compassion, compared to male residents. Among the evaluated dimensions, the residents at the pediatrics and internal wards had more compassion satisfaction, whereas the residents in surgery and emergency medicine wards had the highest rate of job burnout.

The purpose of the present study is to validate the findings of a qualitative research on explaining the mental disorders of suicidal men through modeling and confirmatory factor analysis.

The findings were identified in four main themes including causes of suicidal tendency, empirical consequences, reasons for choosing life, and spiritual perspective and Subsidiary themes include external pressures, interpersonal factors, psychosomatic problems, pervasive feeling, religious beliefs, love for the child, fear of death, responsibility, a positive view of spirituality, remorse, protest and a departure from spirituality, was achieved.

In order to validate the findings, each sub-theme is introduced as a factor and for each factor, a statement that measures the validity of the factor is identified. Finally, a questionnaire with 12 items was prepared and after approval by 15  experts, 93 men from mental hospials of Kerman with suicidal ideation who obtained the required score from the BSSI questionnaire were given to express their opinion in the likert range. After entering the answers into SPSS software, a suitable model was designed and this model was analyzed by confirmatory factor analysis with PLS software.

Finally, the results showed that the findings of the study were validated, reliably and reliably through a questionnaire survey. Following this validation, the results of this study can be used and applied in other studies as well as designing and developing therapeutic protocols with the target population of men with a suicidal tendency that is applicable in the therapeutic group.

Many studies indicated disorders in marriage is an important factor in hospital admission for mental disorders. The purpose of this study was to determine mental health and stress of divorced women in Shiraz mental hospitals.

The present study was conducted on the basis of phenomenological theory in cases from Shiraz mental hospitals. The statistical population consisted of all cases in hospitals and documents related to the perception of mental health and stress of divorced women.

Associations between mental disorders and subsequent marriage and divorce were estimated in discrete time survival models for the cases which refer to a psychiatric hospital. In the first phase, the sample includes a review and review of all indexed books and articles related to the perception of mental health and stress level of divorced women to manage their problem and improve their mental health or reduce the stress. Next, the number of samples was determined according to the theoretical saturation approach.

 Concussion:

The qualitative findings reported from the interviews showed that the mental health and stress of divorced women is associated with numerous problems in physical-psychological-social dimensions. So, it is necessary for the mental hospitals to take the needed steps to ensure that requirements encompassing prevention and promotion of mental health are implemented.

The increase in the number of patients in hospitals and the long wait due to overcrowding are some of the main concerns in health system research. Transferring patients to emergency departments is one way to reduce the congestion of the emergency department.

This study deals with the allocation of patients in the emergency department of hospitals, according to the segregation of the type of disease, which reduces the congestion by transferring patients to other hospitals, if necessary, and minimizes the total cost of the system. In this paper, a linear model is presented for patient allocation and the model is solved using GAMS software.

Patients admitted to the hospital are divided into different types in terms of the type of disease. To reduce the cost of waiting and reduce the waiting time for patients, patients who cannot be treated at the hospital due to lack of expertise in their illness are transferred to other hospitals. All costs, including the cost of increasing the patient's capacity, the cost of admitting the patient, the cost of transporting patients, the cost of waiting fines, the cost of unmet demand and the cost of overtime are calculated in the mathematical model.

by transferring patients, the number of expected patients and the number of patients who are considered as unmet needs can be reduced. Because with the increase in the number of patients waiting and patients who have not been considered as an unmet demand, the mortality rate, medical errors and patient dissatisfaction will increase and irreparable risks will arise, especially for patients with acute problems.

A large number of KRAS mutations in codons 12 and 13 exons two have been reported in gastric cancer (GC). This study aimed to investigate the frequency of codon 12 and 13 mutations in the KRAS gene in patients with gastric cancer in northern Iran.

This is a descriptive cross-sectional study that was performed on patients referred for an endoscopy to Imam Khomeini Hospital in Sari, from 2009-2015. The sample size was assumed to be 100 people. Of the 100, 50 were isolated with a healthy tissue sample and placed in a group based on endoscopic results. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used to evaluate codons 12 and 13 of KRAS gene located in Exon No. 1 of this gene. Statistical tests were performed using SPSS version 24.

In this study, for both codon 12 and codon 13, in cancerous tissue samples, the results were normal and no mutations in the KRAS gene were found. Also, in the normal samples obtained from the patients, the study of codon 12 and 13 in the KRAS gene did not show any change. No mutations in nucleotide G in KRAS gene were found in patients.

The results of the present study showed that there was no association between codon 12 and 13 mutations in the KRAS gene with GC.