مجله دانشکده پزشکی اصفهان
پیاپی 670 (هفته دوم تیر 1401)

Diabetes mellitus is one of the most common chronic diseases in adults that is related to many factors including nutrition habits. In this study, we aimed to compare the frequency of nutritional behaviors between diabetic and healthy adults.

This cross-sectional study was performed on middle-aged people (30-59 years) referred to primary health care centers in Isfahan city between 2015-2016. Two groups with 245 diabetics and 735 non-diabetics were included through convenient sampling and their nutritional behaviors were compared between them.

The desirable consumption of dairy products is less common among diabetic patients. According to the multiple logistic regression analysis, undesirable consumption of fruit &vegetables, dairy products, fatty acids, and carbonated beverages are significantly associated with increased chances of diabetes mellitus (OR = 1.97, 26.97, 4.6, 2.01 respectively).

The change in nutrition pattern in the communities can increase the chance of developing diabetes mellitus, however further studies are needed to evaluate risk factors in diabetic patients.

Headaches are a side effect of nitrates that limits the use of this drug in some patients. The aim of this study was to determine the effect of aromatherapy and lavender essential oils on the prevention of headache induced by infusion of Nitroglycerin in cardiac care units.

In this randomized clinical trial, 45 patients with heart disease were selected by convenience sampling and randomly assigned into 3 groups. In the intervention groups (roses and lavender), as soon as the infusion of nitroglycerin was started, cotton submerged in 3 drops of the essential oil was inhaled for half an hour and no aromatherapy was used in the control group. The frequency of headache was measured by using visual analogue scale at 90 minutes after aromatherapy. In case of headache in any of the groups, usual treatment of headache, acetaminophen tablet 325 mg, was used. This was also recorded in the patient's checklist. Data were analyzed by SPSS at the significant level of 0.05.

The frequency of headache during the study period was not statistically significant in the three groups. However, the amount of acetaminophen used to relieve headache in the rose group was less than the control and lavender groups significantly.

Aromatherapy with rose and lavender essential oils may reduce the headache caused by infused nitroglycerin. Therefore, it is recommended to be considered as one of the effective treatments.

Rheumatoid arthritis (RA) is an autoimmune disease of inflammatory origin. Nowadays, anti-inflammatory effects of medicinal plants are considered as an appropriate alternative to anti-inflammatories drugs. In traditional medicine, different elements of Capparis Spinosa L have been frequently used for treating various diseases. This study was performed to assess the protective effect of hydroalcoholic extract of capparis spinosa root on inflammatory factors of rheumatoid arthritis in rats.

Rats were randomly divided in to 5 groups (n = 6). Rheumatoid arthritis was induced in male wistar rats using Freund’s complete adjuvant (FCA) in the paw planter surface of the rats right hind foot. Methotrexate and Caper root extracts (3, 100 and 300 mg/kg) were administered intraperitoneal daily for 14 days. At the end of period, animals were sacrificed and then serological and hematologic parameters were evaluated.

Serum levels of Tumor necrosis factor α (TNF-α), Interleukine-6 (IL-6), C-Reactive protein (CRP), Anti-Cyclin Citrullinated (Anti-CCP), Rheumatoid factor (RF), and levels of erythrocyte sedimentation rate (ESR), Neutrophil, Lymphocyte, white blood cell and platelets, was significantly elevated in the rheumatoid arthritis group compared to the normal group while significantly decreased in treatment groups compared to the rheumatoid arthritis group (P < 0.001). The mean of red blood cell, hemoglobin, and hematocrit were significantly decreased in rheumatoid arthritis group compared to the normal group and were significantly higher in the treatment groups with caper root compared to the rheumatoid arthritis group (P < 0.001).

Inflammation plays an important role in the process of rheumatoid arthritis. Unlike methotrexate, with extensive side effects, extract of caper root with anti-inflammatory effect, reduces inflammatory factors and provides relative improvement of arthritis status and anemia in rats with rheumatoid arthritis.