مجله دانشکده پزشکی اصفهان
پیاپی 712 (هفته چهارم اردیبهشت 1402)

New technologies in neuroscience like neurofeedback (NFB) is one of the growing and challenging issues. The aim of present study was to determine the effectiveness of NFB on the severity of gastrointestinal (GI) symptoms, depression, anxiety, stress and quality of life in irritable bowel syndrome (IBS).

This study is a double-blind clinical trial with a control group. Initial screening included 160 patients with IBS who were referred by the gastroenterologist. Thirty patients were randomly assigned to three groups of NFB intervention; placebo (Pseudo-NFD) and control group (GI drugs only). The groups completed the IBS Severity Scale (IBS-SSS), Depression, Anxiety and Stress Scale (DASS-42) and IBS Quality of Life Questionnaire (QOL-IBS) before and after the intervention. Data were analyzed using ANOVA.

The results showed that NFB and placebo had a greater and significant effect on reducing depressive symptoms and IBS severity compared to the drug alone (P < 0.05). The placebo group with the drug showed an increase in higher quality of life scores than the other groups (P < 0.05). There was no significant difference between the groups in stress and anxiety.

Findings support the use of NFB along with medication for IBS patients, which is associated with appropriate therapeutic relationship, to enhance the effectiveness of interdisciplinary interventions.

Surgical Site Infection (SSI) after neurosurgical procedures is one of the most common types of hospital infection, on which different results have been reported regarding the effect of antibiotic use. This present study investigated the effect of vancomycin and cefazolin in preventing SSI after elective craniotomy.

The present double-blind interventional clinical trial. Which was done among 126 participants (63 vancomycin group and 63 cefazolin group). The criterion for measuring wound infection was CRP (C-reactive protein) and ESR (Erythrocyte sedimentation rate) on the first and fifth day after surgery, patient's clinical symptoms and wound. Data were analyzed with Chi-square and Independent t-test.

In total, two groups of 9 people got infections after surgery, among which 6 people (67%) were in the cefazolin group and 3 people (33%) were in the vancomycin group. The mean CRP on the first and fifth days in the cefazolin group was significantly higher than the vancomycin group. There were no significant differences in the study groups in terms of length of hospitalization after infection, interval between surgery and time of infection, ESR at the time of infection, length of operation (hours), type of infection and type of organism.

According to the results, there was no difference between the use of cefazolin and vancomycin in reducing the rate of surgical site infection. The rate of surgical site infection in in this study was higher compared to the results of other studies.

Epidemic diseases and their spread are considered a great threat to human health, which leads to adverse mental health effects due to the occurrence of severe changes in life, this study aims to explore the experience of stigma among medical staff. The frontline of the fight against Corona was done.

The present qualitative research was conducted using the hermeneutic phenomenological method, emphasizing Van Manen's method in Bo Ali Sina therapeutic training center in Qazvin city. This research lasted from the beginning of November to the beginning of February 1400, the participants were interviewed by purposeful sampling method until the data saturation stage was reached.

The study showed that the participants experienced three types of social stigma, dependent and self-stigma. First, 190 codes were extracted, and after reduction, elimination, and mergers, 130 initial codes remained finally, by analyzing the information, 8 classes, 63 sub-classes, and 4 within the topic of "own stigma, social stigma, the stigma of family and compatibility with the stigma It was extracted.

The participants in the study pointed out the reduction of cooperation in the workplace due to less exposure to patients with COVID, as well as changes in mood such as fear, stress, anxiety, and anger, and a decrease in self-confidence and feeling of shame, etc., caused by stigma.