International Journal of new Chemistry
Volume:10 Issue: 3, Autumn 2023

This study aims to develop a promising electrochemical sensor based on polymer film overoxidation following the electrochemical polymerization of p-aminophenol on a bare glassy carbon electrode (GCE) surface for the voltammetric determination of acetaminophen (ACP). Cyclic voltammetry (CV) and scanning electron microscopy (SEM) were employed to characterize the electroanalytical performance and morphology of the modified electrode. The results indicated a significant improvement in electrode sensitivity to ACP after electrochemical polymerization and overoxidation of poly(p-aminophenol). We also investigated the effect of all effective instrumental and experimental parameters on sensor response. The electrode SWV response to ACP within the range 0.07-100.0 μmol L-1 with a limit of detection (LOD) of 0.021 μmol L-1 was linear under optimized conditions. We also attempted to evaluate the designed sensor selectivity to different interfering species, suggesting no significant interference. The designed sensor was also used to determine ACP in different pharmaceutical preparations and biologic samples with minimal matrix effects, admissible recoveries (99-106), and satisfactory repeatability (1.0-5.3 %RSD). The proposed sensor exhibited admissible repeatability, reproducibility, and stability.

Metal ions are naturally occurring inorganic substances required in humans in a certain amount by mg/day. They are essential components of biological structures and have an important effect on and play a key role in a variety of the process necessary for life throughout mediating vital biochemical reactions. The role of essential nutrient metal ions as (Na+, K+, Ca2+, and Mg2+) often deficient in our food stuffs, its vitally essential in the function of the human body. Excessive levels, a level higher than needed for biological functions, of these elements can be toxic for the body health. Therefore, it has been found that the imbalances in the optimum levels of trace elements may adversely affect biological processes and are associated with many fatal diseases..In the recent study, 15 samples from deferent patients in ages (18-45) and deferent living environments have been taken from Hawari hospital Kidney division, Benghazi, Libya. The samples were treated by separation of serum from the blood without any chemical treatment. The studied values were measured by spectrophotometer as element analysis. The studied values for metal ions (Na+, K+, Ca2+, and Mg2+) in serum samples, clearly reflect the lack of healthy food taken by the patients, which have caused some decrease in the normal values, even though still under control. The results showed a satisfactory values comparing with the normal values confirmed by WHO.

Magnesium ferrite was used to catalyse the cannizaro reaction of benzaldehyde in the presence of potassium hydroxide. Magnesium ferrite was prepared by hydrothermal process. Similarly Copper, nickel, cobalt, zinc etc. were prepared by same method. It was characterized by Field Emission Scanning Electron Microscopy (FESEM), X-Ray Diffraction Spectroscopy (XRD), and Energy Dispersive X-Ray Spectroscopy (EDX). The crystalline size of magnesium ferrite was found to have 82.47 nm. These magnesium ferrites are nano-flowers in shape. It was found that the yield of the product (benzoic acid) in the presence of Mg ferrite was 49% which is almost 3.4 times the yield obtained in the absence of catalyst. Other metal ferrites were also used as a catalyst but we get higher yield with magnesium ferrite. A comparitive study was made with different metal ferrites as catalyst and found that the activity of metal ferrites followed the order-MgFe2O4 (49%) > CuFe2O4 (46 %) > Ni Fe2O4 (17.05 %) > ZnFe2O4 (5.8 %) > CoFe2O4 (1.1%)

DNA sequences rich in Guanine can come together to form G-quadruplexes, which are tetra-stranded structures. According to some theories, these secondary DNA structures may have a role in the control of several important biological processes. The telomere and the promoter regions of several oncogenes contain guanine-rich sequences that have the potential to create G-quadruplexes in the human genome. The aim of the work was to Prepare guanine complexes with metal ions (Cd(II), Fe(II), Cu(II), Zn(II), Cr(III), Fe(III), Pb(II), and Mn(II)). The complexes were characterised by physical chemical and spectroscopic techniques such as electrical conductivity, metal content, infrared, UV-visible and molar conductivity techniques. The molar ratio of Guanine to metal ion reaction is 1:2, which is determined by the molar ratio method. Dissociation constants for guanine ligands were determined spectrophotometrically. The effect of solvents on the electronic spectra of guanine ligands was studied using solvents of different polarities. The biological activity of guanine ligands and their metal complexes was tested in vitro against selected fungal and bacterial species. The results showed satisfactory spectra for the tested organisms.

This study reports a facile, fast, eco-friendly, and one-pot approach for the synthesis of copper oxide nanoparticles (CuO NPs) using safe Pistacia vera peel extract. The extract is used as a stabilizing and reducing agent. Different analytical technique including FT-IR spectroscopy for determination of the Pistacia vera peel extract functional groups in the reduction and capping process of copper oxide NPs, UV–Vis absorption spectroscopy for affirmation of CuO presence, energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), and X-ray diffraction (XRD) was used in the present study. In these analyses, a sharp peak at 283 nm in UV-vis tests, and a specific Ft-IR peak at 601.59 cm-1 prove that this synthesis was completed using green chemistry principles. In addition, the average size of the biosynthesized nanoparticles was 32.97 nanometers according to the Scherrer equation. CuO NPs antibacterial activity was examined against Bacillus subtilis and Streptococcus pyogenes wherein CuO NPs, exhibited remarkable antibacterial activity with minimum bactericidal concentrations (MBCs) within the range of 125-1000 𝜇g/mL. Additionally, it showed better performance than classical antibacterials in the zone of inhibition assay against Bacillus subtilis. Generally, this study demonstrated that copper nanoparticles synthesized with plant mediators are completely competitive with other chemicals, such as drugs.

AbstractIn this research, density functional theory (DFT) calculations were carried out for investigating the adsorption of the K atom and ion on the surface of three sheet-like nanoparticles, namely nanosheet, corannulene (CRN) and sumanene (SMN). Density of states (DOS) diagrams, geometry optimizations and total energies were all studied using the M06−2X level of theory with the basis set 6−31+G (d, p). The Ead for SMN-i was found to be more negative, which increased in the following order: SMN-i > nano-sheet > CRN-i > CRN > SMN. The main goal of this work was to compute the cell voltage (Vcell) for K−ion batteries (KIBs). Here, the Vcell for SMN was the highest value, which increased in the following order: SMN > CRN > nano-sheet > SMN-i > CRN-i. The current study provided a theoretical description and promising candidate of the above mentioned nano-structures as anode materials in KIBs ion batteries.