Journal of Kerman University of Medical Sciences
Volume:20 Issue: 2, 2013

Post operative pain is cause of suffering in most patients and can cause a lot of problems. Analgesic effects of many narcotics have been widely studied. In this study، the effects of methadone and morphine on postoperative pain scale following thoracic surgery in opium addict patients were assessed.

In this clinical trial and double blind study، sixty opium addict patients (ASA I، II)، aged 20-65 yr، were randomly allocated into two groups. Thirty minutes before induction of general anesthesia the first group received 0. 1 mg/kg methadone and the second group received 0. 1 mg/kg morphine. The two groups were assessed and compared in regard to the intensity of pain and meperidine requirement in the first post operative 24 hr.

Intensity of post operative pain and meperidine requirement in the methadone group were significantly lower than those in the morphine group (P<0. 01).

Administration of 0. 1mg/kg methadone as premedication for opium addict patients reduces the post operative pain more than morphine. Therefore، premedication with methadone for opium addict patients undergoing thoracic surgery is recommended.

Emergence of biofilm producing Proteus strains created a serious problem in the treatment of catheter-associated urinary tract infections. The aim of this research was to study biofilm production and plasmid pattern of proteus strains associated with Urinary tract infection.

A total of 88 strains of Proteus were isolated from samples collected in hospitals of Kerman/ Iran during 2011-2012. The isolates were identified by routin microbiological tests and antibiotic sensitivity tests were carried out by disk diffusion and minimum inhibitory concentration (MIC) by E-test methods. Biofilm production was studied by microtiter plate method and confirmed by Scanning electron microscope. Plasmids from biofilm producing isolates were detected by alkaline lysis technique.

From 88 patients infected by proteus، 58% were female and 42% were male. The most and the least frequent age ranges were respectively 20-29 years old (77. 39 %) and 60-69 years old. From all isolates، 40. 69 % (n=59) showed the highest MIC range (16-32±0. 05 µg/mL) to ceftriaxone whereas، 59% [n=41] exhibited the least MIC range to chloramphenicol (1-4±0. 08 µg/mL). Biofilm production was positive for 17% (n=15) of the isolates and 6% (n=6) did not show any biofilm (P? 0. 05). Plasmid isolation from biofilm producing isolates revealed that stains number 87، 24 and 19 that produced strong biofilm all carried similar high molecular weight (M. Wt) plasmid. While strain 29 that showed strong biofilm did not have any plasmid.

It can be concluded that the majority of isolates of Proteus were resistant to routine antibiotics and limited number of them could produce biofilm. Majority of the biofilm producing isolates contained a similar high M. Wt. plasmid.

Date syrup is a natural sweetener rich in antioxidants. In addition، fructose is the predominant sugar in date syrup، which elevates blood glucose at a slower pace than the other types of sugar. The objective of this study was to evaluate the glycemic response of healthy persons to dietetic sour cherry jam prepared with date syrup.

In this clinical trial، the glycemic response of 9 healthy persons was evaluated after the consumption of two kinds of jams، one prepared with date syrup and one as a control. Both jams had been produced using a specific formulation. White bread was chosen as the reference food. Having determined the glycemic index (GI) of the two jams، glycemic load (GL) was calculated and compared for the two jams by independent t-test.

GL was 15. 4 and 18 for the dietetic and control jams respectively، both of which were within the permitted range for diabetic''s consumption. No significant difference was observed between the GIs of the two jams. The results showed that، the GL of the dietetic jam was significantly lower than that of the control (p<0. 05).

The GL of the dietetic jam prepared with date syrup was less than that of the control sample. In light of the other health benefits of date syrup، once confirmed by further studies، this jam may be suitable to be introduced to the public as a dietetic product.