فهرست مطالب

International Journal of Preventive Medicine
Volume:5 Issue: 4, Apr 2014

  • تاریخ انتشار: 1393/02/25
  • تعداد عناوین: 20
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  • Ozra Tabatabaei-Malazy, Mostafa Qorbani, Tahereh Samavat, Farshad Sharifi, Bagher Larijani, Hossein Fakhrzadeh Pages 373-393
    More than 80% cardiovascular disease (CVD) is preventable despite the fact that it is currently the ultimate cause of disability in the world. Assessment of the nationwide prevalence of dyslipidemia as a major CVD risk factor is essential to efficiently conduct prevention programs. We extracted data according to the cut‑off points of dyslipidemia used in each study. All published papers on this topic in Iranian and international journals with affiliation of “Iran” were reviewed using standard keywords up to September 2011. We included all available population‑based studies and national surveys conducted in individuals aged ≥ 15 years. We excluded studies with < 300 individuals, non‑population‑based studies, or duplicated citations. We analyzed by random effect method due to between‑study heterogeneity. The estimated prevalence and 95% confidence intervals in 29 eligible articles and one un‑published data for hypercholesterolemia (≥200 mg/dl),hypertriglyceridemia (≥150 mg/dl), high levels of low density lipoprotein cholesterol ([LDL‑C] [≥ 130 mg/dl]) and low levels of high density lipoprotein cholesterol ([HDL‑C] <40 mg/dl in males, <50 mg/dl in females), in Iranian people were 41.6% (36.1‑47.0), 46.0% (43.3‑48.7), 35.5% (24.0‑47.1) and 43.9% (33.4‑54.4), respectively among both sexes and in both rural and urban areas. Hypercholesterolemia, high LDL‑C and low HDL‑C were more prevalent in women, whereas hypertriglyceridemia was more prevalent in men. All types of lipid component abnormalities were more prevalent in urban residents. Prevalence of dyslipidemia is considerable in Iran. It is necessary to enforce current measures of dyslipidemia control in the Iranian people to reduce CVD burden.
    Keywords: Cardiovascular disease, dyslipidemia, Iran
  • Mohsen Minaiyan, Behzd Zolfaghari, Diana Taheri, Mahdi Gomarian Pages 394-404
    Background
    Acute pancreatitis (AP) refers to afflicted inflammation of pancreas with unfavorable adverse effects and developed multiple organ failures. Unfortunately, there is not a certain therapeutic method for this disease. Oxidative stress has a serious role in the pathogenesis of AP. Thus, decreasing of oxidative stress may prevent induction and progression of AP. Punica granatum L. has been extensively used in traditional medicine and possesses various active biological elements. Due to antioxidant and anti‑inflammatory properties of pomegranate, it could be considered as a good candidate alternative medicine with beneficial effects on AP. In this study, we decided to study the protective effect of three fractions of pomegranate seeds on cerulein‑induced AP.
    Methods
    AP was induced in male Syrian mice by five intraperitoneal (i.p.) injection of cerulein (50 μg/kg) with 1 h intervals. Treatments with pomegranate freeze‑dried powder (PFDP) and hydroalcoholic pomegranate seeds extract (PSE) at doses of 125, 250, 500 mg/kg (i.p.) were started 30 min before pancreatitis induction. Pomegranate seed oil fraction (PSOF) was orally administered (50, 100, 200 µL/kg) and continued for 10 days. Pancreatic tissue was evaluated for histopathological parameters and pancreatic myeloperoxidase (MPO) activity as well as lipase and amylase levels were measured in plasma.
    Results
    The higher doses of three fractions (250 and 500 mg/kgfor PFDP and PSE and doses of 100, 200 µL/kg for PSOF) significantly reduced amylase and lipase activity in serum (at least P < 0.01), pancreatic MPO activity (P < 0.001), edema, leukocyte infiltration and vacuolization in comparison to the control group (P < 0.05).
    Conclusions
    These results propose that pomegranate seeds fractions can prevent and/or treat the AP.
    Keywords: Acute pancreatitis, anti‑inflammatory, antioxidant, preventive therapy, Punica granatum L, seeds
  • Shervin Assari Pages 405-413
    Background
    This study was aimed to investigate the main and buffering effects of positive religious coping on the association between the number of chronic medical conditions and major depressive disorder (MDD) among African Americans, Caribbean Blacks and Non‑Hispanic Whites.
    Methods
    This cross‑sectional study used data from the National Survey of American Life, 2001 and 2003. This study enrolled 3,570 African Americans, 1,438 Caribbean Blacks and 891 Non‑Hispanic Whites. Number of chronic conditions and positive religious coping were independent variables, 12‑month MDD was the outcome and socio‑economic characteristics were controls. We fitted the following three ethnic‑specific logistic regressions for data analysis. In Model I, we included the number of chronic conditions and controls. In Model II, we added the main effect of religious coping. In Model III, we included an interaction between religious coping and number of chronic conditions.
    Results
    Based on Model I, number of chronic conditions was associated with higher odds of 12‑month MDD among all race/ethnic groups. Model II showed a significant and negative association between religious coping and MDD among Caribbean Blacks (odds ratio [OR] =0.55, 95% confidence Interval [CI] =0.39‑0.77), but not African Americans or Hispanic Whites. Model III suggested that, only among Caribbean Blacks, the effect of chronic medical conditions on MDD is smaller in the presence of high positive religious coping (OR for interaction = 0.73, 95% CI = 0.55‑0.96).
    Conclusions
    Although the association between multiple chronic conditions and MDD may exist regardless of race and ethnicity, race/ethnicity may shape how positive religious coping buffers this association. This finding sheds more light onto race and ethnic differences in protective effects of religiosity on mental health of populations.
    Keywords: African Americans, Caribbean Blacks, chronic medical conditions, ethnicity, major depressive disorder, Non‑Hispanic Whites, positive religious coping
  • Rasool Entezarmahdi, Reza Majdzadeh, Abbas Rahimi Foroushani, Mahshid Nasehi, Abolfath Lameei, Kourosh Holakouie Naieni Pages 414-423
    Background
    Despite significant reduction in global disease prevalence, leprosy still has a high rate of disability while its determinants are unfair and many of them are amendable. The objective of this study was to measure inequality of disability in leprosy in Iran.
    Methods
    This was a cross‑sectional study (2006‑2007) on all living people affected by leprosy registered in W. Azerbaijan province health center, Western North of Iran. The outcome of the study was the socio‑economic inequality considering presence or absence of grade 2 disability (G2D) based on the WHO classifications. An extended concentration index decomposition approach was used for analysis.
    Results
    Among 452 cases, 65.3% were male and 67% were affected by the multi bacillary type. Overall G2D was 65.3%. The estimated Concentration Index was −0.0782, showing presence of pro‑poor socio‑economic inequality of G2D, while extended CI estimation (ѵ = 5) was −0.163. Achievement index with coefficient (ѵ = 5) revealed that G2D mean was 16% more than classic mean in the poorest group. The result of decomposition of the existing inequality revealed that, some of the determinants such as receiving mono‑therapy, education, urbanization, and bacillus calmette guerin (BCG) vaccination had shared contribution (67.4%, 61.8%, 59.2%, and 57.5% respectively).
    Conclusions
    This study provided new perspective for the health system to leprosy control considering the significant gap between rich and poor (inequality) regarding G2D disability, and its effective elements in socio‑economic strata. Some effective actions can be considered to reduce the scale of existing inequality.
    Keywords: Disability, inequality, Iran, leprosy
  • Hajar Naji-Esfahani, Mahsa Zamani, Seyed Mohammad Marandi, Vahid Shaygannejad, Shaghayegh Haghjooy Javanmard Pages 424-429
    Background
    Migraine is a neurovascular disorder and any interventions improving endothelial function may contribute to its treatment and prevention of vascular complications like ischemic stroke. Yoga has been shown to have several beneficial effects on cardiovascular systems. However, no randomized controlled studies to date have investigated its effects on endothelial function of migraineurs.
    Methods
    A total of 42 women patients with migraine were enrolled and randomized into either a Yoga exercise group or a control group. The control group received only medication for 12 weeks and the Yoga group was placed in yoga training program in addition to the same medical treatment. Blood test was given from all patients in order to measure plasma levels intercellular adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM) after yoga training program.
    Results
    Totally 32 patients were participated in the final analyses (yoga: n = 18, control: n = 14). By analyzing data between yoga and control groups after the treatment period, there was a significant decreased in plasma level of VCAM in yoga group compare with the control group (15.29 ± 2.1 ng/ml vs. 21.70 ± 3.0 ng/ml, P < 0.05), whereas there was no significant difference in ICAM level between groups (19.1 ± 1.8 ng/ml vs. 20.97 ± 1.9 ng/ml P > 0.05).
    Conclusions
    It seems that yoga exercises, as a complementary treatment beside pharmacological treatments, can be potentially an effective way of improving vascular functions in migraineurs.
    Keywords: Asana, endothelial function, pranayama, yoga
  • Seema Kapoor, Jay Gopal Ray, Pranav Sikka, Niharika Swain Pages 430-438
    Background
    Human papillomavirus (HPV) and p53 alterations are speculated to play a role in carcinogenesis. This study was carried out to find out the association of HPV and p53 with precancerous lesions of the oral cavity such as leukoplakia: The objective of this study was to find the association among human papilloma virus (HPV) 16 infections and p53 polymorphism in tobacco using the oral leukoplakia patients.
    Methods
    A total of 91 oral leukoplakia patients and 100 controlswere randomly selected from the out‑patient department of atertiary care dental hospital of North‑east India. Blood samples were drawn incisional biopsy was performed from the lesion proper and the tissue was processed for histopathological grading. Cytological smears were taken from the lesional site of leukoplakia patients and buccal mucosa of controls. The rate of HPV infection and p53 polymorphism was detected with the help of polymerase chain reaction, gel electrophoresis and deoxyribonucleic acid sequencing.
    Results
    The rate of HPV 16 infection was found significantly high in the oral leukoplakia patients. No particular p53 genotype at exon 4 of codon 72 was found to be associated with oral leukoplakia, but “C” allele (proline) at exon 4 of codon 72 was significantly raised in these patients.
    Conclusions
    Oral leukoplakia, a well‑known pre‑cancerous lesion, has been shown to be associated with tobacco, but certain other factors like HPV infection and p53 polymorphism may play an important role in its development.
    Keywords: Human papilloma virus, oral leukoplakia, p53 polymorphism, tobacco
  • Zatollah Asemi, Mansooreh Samimi, Zohreh Tabassi, Ahmad Esmaillzadeh Pages 439-446
    Background
    Increased requirement and decreased dietary intakes of micronutrients during pregnancy might affect maternal health and pregnancy outcomes. This study was aimed to examine the effects of two types of multiple micronutrient supplementations on pregnancy outcomes in Kashan, Iran.
    Methods
    In a randomized single‑blind controlled clinical trial, 104 primigravid singleton pregnant women aged 18‑30 years were randomly assigned to receive either a multivitamin (n = 51) or a multivitamin‑mineral (n = 53) supplements for 20 weeks. Participants consumed supplements once a day at week 16 of gestation. Maternal anthropometric data as well as newborn’s weight, height, head circumference and 5‑min Apgar score were also determined. Independent samples t‑test was used for comparing between‑group means. Multivariate linear regression analysis was used to identify determinants of newborn’s weight, height and head circumference.
    Results
    Women taking multivitamin‑mineral supplements gained marginally less weight until week 28 than those taking multivitamin supplements (weight at week 28 of gestation: 67.5 ± 11.4 vs. 71.6 ± 10.3 kg, P = 0.06). Mean body mass index at week 28 (25.8 ± 4.0 vs. 28.4 ± 3.7 kg/m2, P = 0.001) as well as at delivery (28.0 ± 3.9 vs. 30.1 ± 3.8 kg/m2, P = 0.006) was lower among women taking multivitamin‑mineral supplements than those taking multivitamin supplements. Although no significant difference was seen in newborns’ height and Apgar score between the two groups, mean birth weight (3.3 ± 0.4 vs. 3.1 ± 0.4 kg, P = 0.04) and head circumference (35 ± 1.4 vs. 34 ± 1.3 cm, P < 0.0001) of the infants whose mothers receiving multivitamin‑mineral supplements were higher than those whose mothers received multivitamins. Multivitamin‑mineral use by pregnant women was a significant predictor of infants’ weight (β =0.191, P = 0.03) and head circumference (β =0.907, P = 0.005).
    Conclusions
    In conclusion, we found that birth weight and head circumference was increased in infants whose mothers received multivitamin‑mineral supplements for 5 months during pregnancy compared with infants whose mothers received multivitamin supplements.
    Keywords: Birth head circumference, birth weight, multivitamin, multivitamin‑mineral, pregnancy outcome
  • Sayed Hossein Davoodi, Marjan Ajami, Seyyed Abdulmajid Ayatollahi, Kamran Dowlatshahi, Gholamali Javedan, Hamidreza Pazoki-Toroudi Pages 447-456
    Background
    Finding new tolerable methods in weight loss has largely been an issue of interest for specialists. Present study compared a novel method of calorie shifting diet (CSD) with classic calorie restriction (CR) on weight loss in overweight and obese subjects.
    Methods
    Seventy‑four subjects (body mass index ≥25; 37) were randomized to 4 weeks control diet, 6 weeks CSD or CR diets, and 4 weeks follow‑up period. CSD consisted of three phases each lasts for 2 weeks, 11 days calorie restriction which included four meals every day, and 4 h fasting between meals follow with 3 days self‑selecting diet. CR subjects receive determined low calorie diet. Anthropometric and metabolic measures were assessed at different time points in the study.
    Results
    Four weeks after treatment, significant weight, and fat loss started (6.02 and 5.15 kg) and continued for 1 month of follow‑up (5.24 and 4.3 kg), which was correlated to the restricted energy intake (P < 0.05). During three CSD phases, resting metabolic rate tended to remain unchanged. The decrease in plasma glucose, total cholesterol, and triacylglycerol were greater among subjects on the CSD diet (P < 0.05). Feeling of hunger decreased and satisfaction increased among those on the CSD diet after 4 weeks (P < 0.05).
    Conclusions
    The CSD diet was associated with a greater improvement in some anthropometric measures, Adherence was better among CSD subjects. Longer and larger studies are required to determine the long‑term safety and efficacy of CSD diet.
    Keywords: Calorie shifting diet, calorie restriction diet, obesity, resting metabolic rate, weight loss
  • Mubashir Zafar Pages 457-462
    Background
    Cigarette smoking is the largest preventable risk factor for morbidity and mortality in developed countries where at least one in four adults smoke cigarettes. Healthcare providers who smoke are less likely to advise patients to quit smoking. The aim of this study is to find out the frequency of tobacco smoking among medical professionals in tertiary care hospitals of Karachi, and to identify the common factors responsible for the continuation of smoking among healthcare providers.
    Methods
    This descriptive cross‑sectional study was carried out at public and private tertiary Care Hospitals/Institutes at Karachi. A self‑administered questionnaire was used to collect data from 180 subjects. An informed consent was obtained from all the subjects. The data were analyzed using SPSS version 16.0.
    Results
    Prevalence of smoking was 29%. High prevalence of smoking was among male doctors as compared to female doctors. Sixty‑eight per cent of smokers started smoking between 20 to 30 years of age. Age less than 35 years, male and public sectors hospitals were more likely OR 1.23, CI (0.98‑2.41), 6.40 CI (4.48‑10.52) and 2.61 CI (2.20-3.78) respectively.
    Conclusions
    The Result of the study suggests that while healthcare smoking habits appear to be high, they are not uniformly low when compared from an international perspective. Health promotion programs focused on self‑efficacy may be an effective tool for reducing the initiation, frequency, and amount of cigarette smoking among healthcare providers.
    Keywords: Cigarettes, healthcare providers, prevalence, smoking, tobacco
  • Leila Ghahremani, Reza Faryabi, Mohammad Hossein Kaveh Pages 463-471
    Background
    Malaria is one of the most serious diseases in pregnant women as well as children less than 5 years around the world. The present study aimed to investigate the effect of health education based on the protection motivation theory on malaria preventive behaviors in the households of Ghale Ganj, Kerman, Iran in 2011.
    Methods
    The present quasi‑experimental study was conducted on 144 households covered by 8 health centers of Ghale Ganj, Kerman. The study samples were selected through systematic random sampling and the study data were collected using a questionnaire including demographic information, the constructs of the protection motivation theory, and a checklist for assessing the malaria preventive behaviors. After the pre‑test, the intervention group underwent an educational intervention and after two months, the post‑test was performed through the same questionnaire. Then, the data were entered into the SPSS statistical software (v. 18) and analyzed using Chi‑square and Wilcoxon non‑parametric tests. Besides, P < 0.05 was considered as statistically significant.
    Results
    Before the intervention, no significant difference was found between the two study groups regarding perceived vulnerability, perceived severity, response costs, self‑efficacy, response efficacy, and malaria preventive behaviors. After the intervention, however, a significant increase was observed in the intervention group’s mean scores of all the constructs of the protection motivation theory as well as malaria preventive behaviors (P < 0.01).
    Conclusion
    According to the findings of the study, educational intervention based on the protection motivation theory is highly effective in promoting malaria preventive behaviors.
    Keywords: Health education, malaria, protection Motivation Theory
  • Kazem Tarzamni, Manouchehr Khoshbaten, Shohreh Sadrarhami, Parnaz Daneshpajouhnejad, Javad Jalili, Masoud Gholamian, Zahra Shahmoradi Pages 472-477
    Background
    We tested whether hepatic haemodynamics assessed by Doppler ultrasonography can be a predictor of response to therapy in patients with non‑alcoholic fatty liver disease (NAFLD) to prevent further unnecessary diagnostic tests and interventions.
    Methods
    Forty eight consecutive patients affected by NAFLD, who refered to some clinics in Tabriz, Iran between 2009 and 2011 were included in the study. Response to therapy was assessed by decrease in liver enzyme levels. Three liver Doppler parameters (hepatic artery resistance index [RI], hepatic artery pulsatility index [PI] and portal vein waveform [PVW]) were analysed in all subjects who showed a decrease in liver function tests results. Wilcoxon and paired student’s t‑test were used for analysis.
    Results
    Forty eight subjects with NAFLD were included in the study during 21 months, out of which 22 (39.1% male – mean age: 37.6 ± 8.3) responded to the treatment and formed the basis of this study. Mean hepatic artery RI increased significantly from 0.60 ± 0.07 to 0.83 ± 0.27before and after treatment, however, there was no significant differences between hepatic artery PI or PVW.
    Conclusions
    Increase in hepatic artery RI assessed by Doppler ultrasound may provide information on improvement of NAFLD in patients during the course of therapy.
    Keywords: Doppler sonography, hepatic artery resistance index, non‑alcoholic fatty liver disease
  • Mahdieh Kazemzadeh, Sayyed Morteza Safavi, Shahrzad Nematollahi, Zeinab Nourieh Pages 478-488
    Background
    Brown rice (BR) is unpolished rice with various beneficial compounds such as vitamins, magnesium and other minerals, dietary fiber, essential fatty acids, γ‑oryzanol and γ‑aminobutyric acid. In the present study, we compared the effects of white rice (WR) and BR on inflammatory marker high‑sensitivity C‑reactive protein (hs‑CRP) and cardiovascular risk factors among non‑menopausal overweight or obese female.
    Methods
    In a randomized cross‑over clinical trial, 40 overweight or obese (body mass index (BMI) >25) women were randomly allocated to group 1 (n = 20): Treatment with BR diet and group 2 (n = 20): Treatment with WR diet for 6 weeks (first intervention period). Two participants in group 2 dropped out during this period. After a 2‑week washout period, individuals were switched to the alternate diet for an additional 6 weeks (second intervention period) and three subjects in group 2 did not follow this period and eliminated, finally this study was completed with 35 subjects (group 1 = 20 and group 2 = 15). Each one was instructed to consume 150 g cooked WR or BR daily in each intervention period. Cardiovascular risk factors including BMI, waist and hip circumference, blood pressure, serum lipid profiles, fasting blood glucose (FBG) and hs‑CRP as an inflammatory marker, were measured 4 times (in study week 0, 6, 8, 14).
    Results
    BR diet in comparison with WR diet could significantly reduce weight, waist and hip circumference, BMI, Diastole blood pressure and hs‑CRP. No significant differences between the two diets were found regarding lipid profiles and FBG.
    Conclusions
    The present results suggest that BR replacement in the diet may be useful to decrease inflammatory marker level and several cardiovascular risk factors among non‑menopausal overweight or obese female.
    Keywords: Brown rice, female, inflammation, obese, overweight, white rice
  • Samad Ej Golzari, Hassan Soleimanpour, Hamidreza Mehryar, Shaker Salarilak, Ata Mahmoodpoor, Jafar Rahimi Panahi, Mohammadreza Afhami, Majid Sabahi, Zahra Hassani Pages 489-493
    Background
    Increasedlife expectancy in populations has brought along specific new scenarios in the fields of medicine for the elderly; prevalence of physical complications such as edentulism and patients with dentures is growing. Management of anesthesia and ventilation in this group of patients has turned into a great challenge. Some researchers suggest dentures to be left in place during bag‑mask ventilation; yet, no unanimous agreement exists in this regard.
    Methods
    In a single blind randomized clinical trial, we studied 300 patients with ASA class I, II (American Society of Anesthesiologists), Mallampati class (I, II) and aged over 55 years in three groups. After induction of anesthesia, in group G dentures were removed and in each buccal space an eight‑layer 10 × 10 cm gauze and an oral airway were placed. In group D, the dentures and an oral airway were left in place. In group C (control), after removing dentures just an appropriate oral airway was placed. Then, each three group underwent bag‑mask ventilation. Success of bag‑mask ventilation (BMV) was considered as increase in end‑tidal carbon dioxide to more than 20 mmHg and back to baseline with fresh gas flow of 3 L/min and adjustable pressure limiting valve pressure of 20 cm H2O. Success rates were evaluated between groups.
    Results
    Effective BMV was possible in 91 (91%), 64 (64%) and 41 (41%) patients in groups G, D and C respectively. The differences were statistically significant. Successful BMV rate was significantly higher in female patients in group G compared to group C; 43/44 versus 25/46 individuals, P = 0.0001, odds ratio = 0.03, 95% confidence interval (0.00, 0.22).
    Conclusions
    Leaving dentures in place in edentulous edentulous patients after inducing anesthesia improves bag‑mask ventilation. However, placing folded compressed gauze in buccal space leads to more significant improvement in BMV compared to leaving dentures in place.
    Keywords: Bag‑mask ventilation, dentures, edentulous patients, end‑tidal carbon dioxide, folded gauze
  • Syed Sadat Ali_S. M Dhaded_Shivprasad S. Goudar Pages 494-499
    Background
    In India, child malnutrition is mostly the result of high levels of exposure to infection and inappropriate infant and young child feeding and caring practices and has its origins almost entirely during the first 2 to 3 years of life. This study aims in assessing the impact of breast feeding on child development of children at 3 years.
    Methods
    About 530 children at 3 years were assessed for developmental delay by Ages and Stages Questionnaire (ASQ). Growth measurements and hemoglobin estimation were carried out at the time of developmental evaluation. Physical growth was assessed by using World Health Organization growth charts. Children were assessed for their duration of breast feeding and weaning period. They were analyzed for the feeding practices versus developmental outcome. Chi‑square test was used to compare the categorical variables. Differences were considered significant at P < 0.05 level.
    Results
    Children who were exclusively breastfed for at least 6 or more months had significantly higher ASQ scores with P value for communication (0.003), gross motor (0.004), fine motor (0.007) and problem solving 0.013) except personal social (0.059) compared with children who had exclusively breastfed for less than 6 months. Children, who were weaned beyond 12th month, had significantly higher ASQ scores with P value for communication (0.004), gross motor 0.091), fine motor (0.044), problem solving (0.001) and personal social (0.012) as against those who were weaned at 6th month or earlier in all domains.
    Conclusion
    Breast feeding has a positive effect on the overall development of the child and should be promoted in the present generation. In India, c hild malnutrition is responsible for a higher percentage of the country’s burden of disease. Undernutrition also affects cognitive and motor development and undermines educational attainment; and ultimately impacts on productivity at work and at home, with adverse implications for income and economic growth.
    Keywords: Breast feeding, child development, undernutrition
  • Rakesh Kumar Manne, Kannan Natarajan, Rajendra Patil, Venkata Sarath Prathi, Beeraka Swapna, Suneel Kumar K.V Pages 500-504
    Glanzmann’s thrombasthenia (GT) is an autosomal recessive inherited platelet function defect characterized by normal platelet count, prolonged bleeding time and abnormal clot retraction. This disease typically presents in infancy or early childhood and has proven to have very good prognosis. In this case study, a 22‑year‑old GT patient who also developed human immunodeficiency virus (HIV) infection after sometime is reported. The patient showed oral manifestations of gingival hyperplasia and petechial lesions. Unfortunately the detection of both thrombasthenia and HIV were done at considerably late stages which contributed to a poor prognosis. The patient died of cardiopulmonary arrest secondary to HIV, thrombasthenia and thrombocytopenia. The importance of early detection, supportive care and communication between the general and oral physician in management of the GT is also discussed.
    Keywords: IIb, IIIa glycoprotein complex, gingival hyperplasia, Glanzmann thrombasthenia, human immunodeficiency virus, thrombocytopenia
  • Shirin Djalalinia, Parviz Owlia, Hossein Malekafzali, Mostafa Ghanei, Abdolreza Babamahmoodi, Niloofar Peykari Pages 505-510
    Background
    Planning, organizing, staffing, leading and monitoring are the basic functional component of management. In present article, we aim to define the project monitoring and evaluation in health research system (HRS) considering its success and challenges based on our national experience.
    Methods
    In this study based on the information of annual Medical Science Universities evaluation during the last decade the HRS indicators have been scored in three axes based on HRS functions: Stewardship, capacity building and knowledge production. In this article, we will focus on the results of HRS evaluation from 2002 to 2010, also on its success and challenges.
    Results
    In an overall view, the main results are the experiences of the designing and implantation of such process after pre‑project preparation, all parts followed under the whole supervision of the aims of the HRS evaluation. Project management light the way of practical application of knowledge, skills, tools and techniques for better HRS evaluation and management.
    Conclusions
    We concluded that; although monitoring and evaluation as an essential part of HRS Management light the improvement ahead way but we still need to advantage of the new project management advances.
    Keywords: Evaluation, health research system, management
  • Sharat Gupta, Shallu Mittal, Avnish Kumar, K.D. Singh Pages 511-515
    The study was conducted on a group of 90 traffic policemen aged 20-50 years and working in and around Patiala district to assess their knowledge, attitude, and practices toward the ill effects caused by traffic noise on health. The subjects were required to fill up a questionnaire regarding their self‑assessment of hearing ability, noise‑related attitudes, and the use of personal protective equipment such as earplugs. The mean age of subjects was 39.8 ± 5.80 years, while the mean duration of exposure to traffic noise was 10.56 ± 6.43 years. Only 5.5% subjects felt that their hearing was below average. As many as 61% subjects had work‑related tinnitus. It was observed that none of them had ever used ear plugs, mainly due to their non availability. The self‑assessment of hearing by traffic policemen indicated that most of them had normal hearing. However, to find out the exact number of cases with hearing impairment, further evaluation with audiometry is recommended in them.
    Keywords: Noise‑induced hearing loss, noise pollution, occupational hearing loss, traffic policemen
  • Olorunfemi Emmanuel Amoran, Albert Adekunle Salako, Olubunmi Jeminusi Pages 516-521
    Background
    Long term exposure to hazards at the work place is injurious to health and usually leads to diseased conditions. The objective of this study was to determine the occupational health problems associated with driving among the professional drivers in Sagamu, Ogun state, Nigeria.
    Methods
    This study is a cross‑sectional study. Total sample of all the consenting professional drivers in the five interstate motor parks, including the cement factory [WAPCO] in the local government area, were recruited into the study. An interviewer administered structured questionnaire was administered by trained health workers and respondents were screen for common occupational health problems.
    Results
    A total of 400 professional drivers were interviewed, all [100%] of them were males with age range from 21 to 59 yrs and nearly half [42%] were non indigenes. Only half, 208 [52%] of them were married with majority, 232 [58.0%] working for about 12 hrs daily and 46% of them had been working for 5 yrs or more. Most, 382 [95.5%] had been educated on HIV/AIDS before and 313 [78.3%] of them had multiple sexual partners. Only 241 [60.3%] used condom at the last sexual act and 55 [13.5%] had ever been tested for HIV/AIDS. Common occupational health diseases were renal tubular acidosis (RTA) 52 [13%] in the last one year and most of them currently have myalgia 352 [88.0%], upper respiratory tract infections (URTI) 20 [5.0%], sexually transmitted diseases (STD) 15 [3.8%], short sightedness 41 [10.3%], and Hypertension 90 [22.5%].
    Conclusions
    The study shows that common occupational diseases among long distance professional drivers in Western Nigeria were myalgia, upper respiratory tract infection, hypertension, short sightedness, sexually transmitted diseases, and RTA. Prevention and control of these common diseases among the drivers will lead to reduction of road traffic accidents in Western Nigeria and other low income countries.
    Keywords: Drivers, Nigeria, occupational diseases, screening
  • Ali Nikfarjam, Nadereh Memaryan, Behzad Damari, Nasim Zamani, Hossein Hassanian-Moghaddam Pages 522-526
    Background
    Evidence shows that in Iran alcohol abuse rate may be of concern, especially among the youth. The mental and social health and addiction Department of the Ministry of Health and Medical Education has designed a plan to prevent, treat, and rehabilitate the patients abusing alcohol in a time period of 2011‑2015.
    Methods
    In a 6‑month period, three guiding committees of experts in the field of alcohol abuse reviewed the literature. The meetings of the steering committee were held in order to collect the comments of the policy‑makers in recognition of the problem, orientation, and administration procedures for the suggested strategies. The first input was discussed in the committee meeting. In the orientation phase, intervention strategies were suggested whose base was the evaluation of the previous international guidelines. In the final phase, the suggested strategies and challenges and their possible solutions were criticized. Finally, using these strategies, appropriate interventions were defined.
    Results
    Preventing alcohol supply, school‑ and community‑based prevention efforts, monitoring and vigilance were defined as primary prevention. While secondary and tertiary prevention are defined to be the treating and rehabilitating services for the alcohol abusers.
    Conclusions
    We hope by using this strategy we will be able to control alcohol abuse in our country. The first step to reach this aim is done by breaking the taboo of giving alcohol‑related information and news using media and educational programs especially to the young population.
    Keywords: Addictive, alcoholism, behavior, prevention, control, primary prevention
  • Masoudreza Sohrabi, Farhad Zamani, Alireza Shirangi, Hossein Ajdarkosh, Hossein Kivani, Mehdi Mohamadnejad Pages 527-528