فهرست مطالب azad reza mansourian

 Okra (Abelmoschus esculentus) has garnered scientific attention for its beneficial effects on various chronic disorders, including type 2 diabetes mellitus.

 The current study was designed and conducted to assess the influence of whole okra fruit powder on the serum levels of specific biochemical parameters in individuals with pre-diabetes.

 Seventy pre-diabetic patients, aged 30 - 55 years, were divided into two groups: The okra group (n = 35, fasting plasma glucose: 116.26 ± 6.02) and the placebo group (n = 35, fasting plasma glucose: 112.26 ± 5.8). The okra group received 3000 mg of okra capsules daily for eight weeks, while the placebo group received placebo capsules. Liver function, renal markers, and lipid profiles were assessed at both the baseline and the end of the experiment using a spectrophotometer. The impact of the okra intervention on biochemical parameters was determined using parametric or non-parametric analysis of covariance (ANCOVA).

 The serum levels of total cholesterol, low-density lipoprotein cholesterol, liver transaminases, and uric acid were significantly lower in the okra group compared to the placebo group. Conversely, the high-density lipoprotein cholesterol levels were significantly higher in the okra group than in the placebo group. However, there were no statistically significant differences between the two groups regarding triglycerides, creatinine, blood urea nitrogen, and alkaline phosphatase levels.

 The consumption of okra effectively improved the lipid profile and certain serum parameters (alanine transaminase, aspartate transaminase, and uric acid) related to liver and kidney health in pre-diabetic participants.

The prevalence of hypothyroidism is much higher among women than in men. Hypothyroidism is also one of the most prevalent thyroid disorders among women of reproductive age. The disease exerts its effect on female sex hormones by manipulating the production of luteinizing hormone and follicle-stimulating hormone that are crucial for the production of estrogen by the ovaries. Various studies demonstrated the adverse effect of overt hypothyroidism on ovulation, menstrual cycle, and fertility. This review surveys the adverse effects of hypothyroidism on fertility and pregnancy.

Thyroid hormones play a key role indevelopment of most metabolic disease. Toxic multi nodular goiter, toxic adenoma and thyroid autoimmunity are the most common causes of thyrotoxicosis. Graves’ diseaseis an autoimmune thyroid disorder characterized by production of autoantibodies against thyroid-stimulating hormone receptor on the thyroid gland.G raves’ disease-related thyrotoxicosis can be controlled either through medication or surgical and radiotherapy interventions. There are few options for the prevention of thyroid hormones overproduction including antithyroid drugs such as methimazole and propylthiouracil, carbimazole, radioactive iodine as well as thyroidectomy. In this study, the latest pharmacological information on treatment of Graveschr('39') disease are reviewed.

The serum levels of various hormones change in patients with chronic renal failure. The aim of this study was to compare the serum levels of hormones and various biochemical parameters before and after hemodialysis.

This study included 111 patients with chronic renal disorder and was conducted in Gorgan's 5 Azar hospital. Blood samples were collected from all patients before and immediately after dialysis to measure T3, T4, FT3, T3UP, TSH, FT4, cholesterol, triglycerides, creatinine, BUN, uric acid and fasting blood sugar.

The results showed that the levels of FT3, FT4 and T3 were significantly increased after hemodialysis; the levels of creatinine, BUN and uric acid were decreased; but the levels of Cholesterol, triglycerides and FBS were shown a significant increase in blood.

Dialysis can improve and augment the levels of thyroid hormones in patients with renal failure. On the other hand, hemodialysis leads to rise total cholesterol and triglycerides and as a result can increase the risk of cardiovascular diseases.