moghimim

The most common methods of extraction of oil from oils seeds are pressing and solvent methods that the most effective method of extracting sunflower oil, like other seeds with high oil content such as rapeseed, is mechanical press and then solvent extraction. In this research, to model the process of oil extraction from sunflower seeds on an industrial scale, three levels cooking temperature (70, 80 and 90 ° C) and three levels of moisture of the output seeds from the cooker (7, 7.5 and 8 %) was used and the amount of oil acidity, the contentt of oil, protein and moisture of meal and the percentage of insoluble fine partical in oil were studied. To predict the change's trend the artificial neural network in MATLAB R2013a software was used. By studying the various networks of back propagation feed forward network with topologies 2-10-5 with a correlation coefficient of more than 0.999 and the mean squared error of less than 0.003 and with using sigmoid hyperbolic of tangent activation function, the Levenberg–Marquardt learning algorithm and learning cycle of 1000 were specified as the best neural model. The results of the optimized and selected models were evaluated and these models with high correlation coefficients (over 0.96), were able to predict the change's trend.

Infantile Fibrosarcoma is a rare soft tissue tumor in infants and children mostly located in extremities. An infantile and adult form has similar histopathological patterns but survival prognosis is much better in infantile form. Recurrence of infantile fibrosarcoma is common but the rates of metastasis are less than 10 percent in children younger than five Years and 50 percent in children more than 10 years old. In this case report, we presented a nine years girl with a relapsing mass in her left hand. The pathologic findings showed sheets of spindle-shaped cells with suggested diagnose of infantile fibrosarcoma. She was successfully treated with combination of surgery and chemotherapy with a good outcome. Infantile fibrosarcoma is a differential diagnose of soft tissue mass in infants and children. It has a good prognosis and distant metastasis is uncommon. Choice of treatment is surgery but chemotherapy and radiotherapy were useful in decrease metastasis.

Lipomas among the most common benign neoplasms and rarely observed in parotid glands. We present a new case of lipoma in the superficial and deep lobes of the right parotid gland.Case report: A 52-year-old woman with painless and progressive inflation in the right preauricular region was referred to us. Computed Tomography scanning showed a hypodense area 5.2×4 cm in dimension in the right parotid gland region, and the facial nerve was fully exposed. The patient underwent parotidectomy, during which extensive removal of the mass was done. The pathology report cited a yellow-colored fatty tissue mass, 5×4×2 in dimension. In the microscopic report, lipoma of the parotid gland was seen. Determination of the exact tumor location is very important in the surgical approach in such cases. To our knowledge, this case seems to be an extremely rare case of lipoma in the superficial and deep lobes of the parotid.

Elevation of the b-HCG serum levels has been reported in several tumors including breast cancer, and it is usually associated with aggressiveness. The aim of this study was to examine the possible correlation between the b-HCG serum levels and different grades of breast cancer tumors in patients undergoing chemotherapy.

This cross-sectional study was conducted in the city of Zanjan during 2009-10. Serum samples from 56 cases of breast cancer patients were collected after surgery and prior to chemotherapy for analysis of total free b-HCG by electro chemiluminescence immunoassay, and the same procedure was repeated after 8 courses of chemotherapy. The b-HCG serum levels were compared in poor versus mild to moderate grades before and after chemotherapy.

In 37 cases of mild to moderate grade tumors, the mean b-HCG level was 1.09 ±1.4 miu/ml compared with 1.2 ±0.3 miu/ml (P= 0.75) in 29 cases of poor grade tumors. The mean b-HCG levels before and after chemotherapy were 1.15 ±1.4 miu/ml and 1.17 ±1.4 miu/ml (P=0.24), respectively.

We did not find any significant association between the b-HCG serum levels and breast cancer tumor grades. Furthermore, chemotherapy does not appear to have an effect on b-HCG serum levels.

About 7% of patient referred to hospital are various forms of poisoning. This study was performed to determine the major causes of acute poisoning leading to Hospitalization at Shahid Beheshti Hospital of Yasuj, Iran.

This descriptive study was performed from August 2007 to July 2008 on 470 cases of poisonings referred to Shahid Beheshti hospital of Yasuj. Demographic characteristics, time of poisoning, poisoning factor, history of previous poisoning, history of psychiatric disease, medication and other therapeutic intervention based on questionnaires and interviews with patients or companions of patients were recorded. Data were analyzed by Chi-Square Test.

Majority of poisoned patients were single females, in the age range of 21-30 years, unemployed, lived in urban areas, and had at least a diploma. The majority of cases were intentional poisoning with a history of depression, previous poisoning and attempted suicide. Significant relationship were seen between poisoning, age, sex, and job, (p<0.05), while relationship between the place of residency, marital status, and education, with poisoning was not significant (p>0.05).

With respect to the results of this study, the majority of these poisonings occurred among young, single and unemployed females due to suicide and drug intoxication. Necessary actions should be done in drug usage and maintenance, taking action against non-prescription drugs and giving proper public education to families.

Gastric cancer is one of the most common cancers in the world that can metastasize to other sites. The most common sites of metastasis are liver, lung, bone, and adrenal glands. Skin metastasis in gastric cancer is rare, and it usually occurs after diagnosis of primary cancer (1). The patient reported here is a 65-years old male with gastric adenocarcinoma that in the course of chemotherapy came down with some skin lesions. The biopsy report points to skin metastasis from gastric cancer. In spite of good systemic response to chemotherapy, the lesions progressed. Skin metastasis has poor prognosis, and it is a sign of disease diffusion (2).

BackgroundLimb gangrene in neonates is an extremely rare clinical problem and very few cases have been recorded up to now. The clinical findings were mild involvement of skin to full necrosis and gangrene of the involved regions. Unfortunately, in most cases the etiology cannot be established. However, a variety of etiological causes may account for this condition.Case PresentationWe present a newborn baby with symmetrical peripheral gangrene of the limbs, both flanks, chin, and scrotum due to leukocytoclastic vasculitis with unknown cause. He was treated by parenteral glucocorticoid, broad-spectrum antibiotics, heparin, hydralazine and fresh frozen plasma (FFP). He died after 2 weeks of intensive treatment. There is history of the same disease in two infants of his paternal aunt, both of them were dead soon after birth.ConclusionPeripheral gangrene with symmetrical involvements, due to vasculitis, is a very unique disorder in newborn infant, which no case was reported up to now.

Introduction & Multiple sclerosis (MS) is a type of progressing and degenerating disease of myelin membrane of nervous cells in the Central Nervous System (CNS) which could cause the incidence of many signs and complications in patients. The disease could affect different aspects of an individual’s life and disturb his/her normal life. This study was carried out in order to survey the effect of yoga exercise on general health status (GHS) and sense of life in patients with multiple sclerosis. This research was a clinical trial study carried out at Yasouj University of Medical Sciences on 60 female patients with multiple sclerosis from Kohgiloyeh and Boyerahmad province in 2009.The data collecting tool consisted was MSQoL-54 questionnaire contained demographic information of patients. Patients were randomly divided into two control and case groups (30 persons in each group). Then, the general health status (GHS) and sense of life of the subjects were evaluated. Yoga therapy was done in the case group for three months and each month included eight sessions of 1-1.5 hours while no intervention was carried out on the control group. One month after Yoga therapy, the general health status (GHS) and sense of life for both groups were evaluated and compared with each other. Collected data were analyzed using descriptive tests, statistical independent t-test and paired t-test by the SPSS software. The mean age of samples was 31.6±8.0 with the range of 18-45 years. Forty two (70%) of the subjects were married and 18 (30%) were single. Forty four (73.3%) had high school education and 16 (26.6%) had a university degree. Regarding occupation, most of them (63.3%) were housewives. Results of the study showed that after Yoga therapy, the mean rate of general health status (GHS) and sense of life as a whole had significant statistical difference between two groups (P<0.05). Yoga has improved the general health status (GHS) and sense of life of multiple sclerosis patients in our study. Considering the less cost, feasibility and rapid learning of Yoga techniques, the training of doing such exercise to patients with multiple sclerosis is recommended.

Gastric cancer is one of the most common cancers in Iran and is one of the most frequent causes of death due to cancer. Despite progresses in treatment, it still causes much mortalities and its treatment is still a matter of debate in the world. This study was performed with the aim of investigating the factors affecting prognosis, the survival rate and effect of different treatments on survival in gastric adenocarcinoma patients. This analytical case series study was conducted on 47 gastric or cardia adenocarcinoma patient referring to Shahid-Ramezanzadeh Radiation Center from 2004 to 2009 and were selected by accessible sampling. Data was extracted from patient's records and follow up was conducted through telephone contacts. Kaplan-Meier curves and SPSS 13 software were used for data analysis. Two-year and three-year survival of patients were 50% and 30%, respectively. Mean survival rate was 29.9 months and mean disease free survival rate was 12.95 months. Survival rate revealed a significant relation with disease stage (p=0.046), performed therapies (p=0.027) and surgical margin. Patients who had received a combination of surgery, chemotherapy and radiation therapy had the best survival. Survival had no relation with type of adenocarcinoma, tumor location or grade and chemotherapy regimen. Age, gender, surgery type, tumor location or grade and chemotherapy regimen do not affect survival, but the disease stage, performed therapies and surgical margin affect it. It seems that a combination of surgery, chemotherapy and radiation therapy would provide the best effect on patent's survival.

Health care workers (HCWs) are at risk of contracting and spreading hepatitis B virus (HBV) and hepatitis C virus (HCV) to others. The aim of this study was to evaluate knowledge، attitudes and behavior of physicians concerning HBV and HCV. A 29-item questionnaire (reliability coefficient = 0. 7) was distributed at two national/regional congresses and two university hospitals in Iran. Five medical groups (dentists، general practitioners، paraclinicians، surgeons and internists) received 450 questionnaires in 2009، of which 369 questionnaires (82%) were filled out. Knowledge about routes of transmission of HBV and HCV، prevalence rate and seroconversion rates secondary to a needlestick injury was moderate to low. Concern about being infected with HBV and HCV was 69. 4±2. 1 and 76. 3±2 (out of 100)، respectively. Complete HBV vaccination was done on 88. 1% of the participants. Sixty percent had checked their hepatitis B surface antibody (anti-HBs)، and 83. 8% were positive. Only 24% of the surgeons often used double gloves and 28% had reported a needlestick. There was no significant correlation between the different specialties and: concern about HBV and HCV; the underreporting of needlestick injuries; and correct knowledge of post-needlestick HBV infection. Although our participants were afraid of acquiring HBV and HCV، knowledge about routes of transmission، prevalence، protection and post-exposure seroconversion rates was unsatisfactory. By making physicians aware of possible post-exposure prophylaxis، the underreporting of needlestick injuries could be eliminated. Continuous training about HBV and HCV transmission routes، seroconversion rates، protection، as well as hepatitis B vaccination and checking the anti-HBs level، is a matter of necessity.

Gastric cancer is the second common cancer in Iran and it has unfortunately no diagnostic signs in early stages. Considering the role of genetic and environmental factors in the development of gastric cancer, this study aimed at evaluating DNA-content of stomach cells in patients with gastric cancer in order to find a reliable index for prediction of disease prognosis and providing more exact therapeutic procedure. A total of 22 samples taken from patients with gastric cancer were evaluated. Peritoneal lavage cells were centrifuged and stained with DNA-staining kit. Then DNA-content was analyzed and compared with that in normal cells by employing flow cytometry and using modfit software. In whole, 12 out of 22 samples were positive and DNA aneuploidy was present in 33.3%. SPF increase was observed in 22.2% of positive cases. SPF can be used as a reliable indicator in pathological staging of cancer and consequently in decision making for treatment.

Severe combined immunodeficiency is a true pediatric emergency; children with SCID were the first patients with immunodeficiencies to be successfully transplanted with unrelated and T-cell-depleted, haploidentical bone marrow. The pattern of inheritance of SCID is X-linked and autosomal recessive (ADA def, Jak3, RAG1, RAG2, IL 7Rα). In this case report, we describe a one-year-old boy with B+T- SCID who received unrelated cord blood transplantation from the Cord Blood Bank in Germany with a 4/6 HLA antigen match. The conditioning regimen was 1mg/kg/day Busulfan and 10mg/kg/day Cyclophosphamide. Both of them were given for two days. GVHD prophylaxis was performed with Cyclosporine A and Methotroxate.Stage III skin GVHD appeared on day 7 and gastric GVHD with a 250-300cc volume appeared on day 8. On day 14, CVP, CRP, LDH and SGOT increased, blood pressure decreased and arrhythmia with T change, AV block, RBBB and bradycardia appeared. With the conclusion of Myocarditis, the patient was treated with diuretics and limitation of liquid intake, Dexamethazone, Dopamine and IVIG. The heart condition was improved gradually. During hospitalization, there was no decrease in platelet count and radiated PRBCS transfusion was performed twice. The patient was discharged on day 60. Donor cell chimerism of 60% was detected with STR-PCR, which was followed up regularly and tapered the immunosuppressive therapy.Unrelated cord blood is a stem cell source in SCID patients and it is a curative treatment in patients without appropriate donors.