decompression
در نشریات گروه پزشکی-
Percutaneous lumbar disc decompression (PLDD) has emerged as an effective and minimally invasive treatment option for lumbar disc herniation. This review aims to provide pain specialists with a comparative overview of Iran’s commonly utilized PLDD techniques: Laser, radiofrequency (RF), and quantum PLDD. The review discusses patient selection criteria, procedural characteristics, and outcomes to facilitate informed clinical decision-making.
Keywords: Low Back Pain, Intervertebral Disc Displacement, Decompression, Minimally Invasive Surgical Procedures -
Background
There is still no standard of care to manage thoracolumbar burst fractures. With all the recent advances, posterior approaches are still one of the mainstays of treatment. On the other hand, while spinal canal decompression in neurological impaired patients is an important goal of treatment, its technique remains controversial.
This study compared the effects of direct laminectomy decompression against ligamentotaxis/indirect canal decompression on neurological and radiographic improvements.MethodsA prospective double-blind randomized clinical trial was conducted on 60 thoracolumbar burst-fracture patients meeting our inclusion and exclusion criteria. They were randomized into 2 treatment arms: (1) direct decompression using laminectomy and (2) indirect decompression using ligamentotaxis/distraction. Each patient was observed for 6 months, and their neurological and radiographical data were collected prospectively. Statistical analysis was done by the Student t test, Friedman test, Mann Whitney-U test, Wilcoxon ranked test, and 1-way analysis of variance.
ResultsAmong 60 patients enrolled in our study, each treatment arm had an improvement in Frankel scores but there was no difference between the groups at any given time. After 6 months of surgery, local sagittal kyphosis improved in both groups (from 32.2 to 7.43 and 29.93 to 8.77 for the indirect and direct groups, respectively), as well as anterior vertebral height ratio (from 57.73 to 70.7 and 62.17 to 66.27 for the indirect and direct group, respectively) and posterior vertebral height ratio (from 61.17 to 74.87 and 64 to 67.5 for the indirect and direct group, respectively). For between-group comparisons after 6 months, there was a significant difference only for posterior vertebral height ratio (P = 0.040).
ConclusionPosterior approaches with ligamentotaxis have shown to be safe and may present the same outcome as direct decompression techniques using wide laminectomy.
Keywords: Ligamentotaxis, Burst fractures, Decompression, Indirect -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هشتاد و یکم شماره 2 (پیاپی 265، اردیبهشت 1402)، صص 125 -133زمینه و هدف
آسیب طناب نخاعی به دنبال تروما از جمله وقایع فاجعه بار محسوب می شود که میزان بروز آن، نسبت به دهه های گذشته در حال رشد بوده است. در مطالعه حاضر بیماران دارای شکستگی های توراسیک و لومبار در دو بازه زمانی کمتر و بیشتر از 24 ساعت مورد بررسی قرار گرفتند.
روش بررسیمطالعه از نوع مقطعی زمانی بوده و بر روی بیماران دارای شکستگی توراکولومبار و توراسیک مراجعه کننده به بیمارستان گلستان اهواز در بازه زمانی خرداد 1398 تا دی 1400 انجام شد. شش ماه پس از جراحی، جهت ارزیابی اندام های تحتانی از تست های برداشتن جسم کوچک با انگشتان پا و دنبال کردن مسیر مستطیل استفاده شد. فورس عضلات پروگزیمال فوقانی و تحتانی نیز برای ارزیابی حرکات Motor gross بررسی شدند.
یافته ها160 بیمار شامل 133 مرد (1/83%) و 27 زن (9/16%) با میانگین سنی 12±36 سال وارد مطالعه شدند. شایعترین محل شکستگی در ناحیه لومبار (1/53%) و پس از آن به ترتیب در ناحیه توراسیک (1/43%) و شکستگی هر دو ناحیه (8/3%) دیده شد. بیشترین مهره اسیب دیده مهره L1 (5/27%) و T12 (8/18%) بوده اند. شش ماه پس از جراحی، بیماران با جراحی زیر 24 ساعت به طرز معناداری دارای بهبودی بالاتری در برداشتن جسم کوچک با انگشت پا، توانایی دنبال کردن مستطیل و میزان بهبودی (امتیاز 5) بوده اند (05/0>P).
نتیجه گیریمطالعه حاضر نشان داد که انجام Decompression زیر 24 ساعت در بیماران دچار TSCI، با بهبود چشمگیر حرکات ظریف تحتانی همراه می باشد.
کلید واژگان: آسیب طناب نخاعی، لومبار، توراسیک، تروما، کاهش فشارBackgroundTraumatic Spinal Cord Injury (TSCI) is one of the catastrophic events, the rate of which has been growing compared to the past decades. Complications caused by TSCI have a wide spectrum and can range from complete paralysis to numbness of the limbs. Additional to the injury severity and disability of the patient, the recovery rate depends on the treatment strategies. Despite extensive efforts and research in this field, there are still few treatment options for TSCI patients. Controversial results have been reported, however, spinal cord decompression is the only certainty for the treatment of these patients. In the present study, patients with thoracic and lumbar fractures were undergone decompression, less and more than 24 hours, and the recovery rate (RR) was compared after 6 months.
MethodsIn this study, patients with lumbar and thoracic fractures who were referred to the neurosurgery department of Ahvaz Golestan Hospital during May 2019 to December 2021 were included. Decompression was performed at the fracture level as a total and at the upper and lower levels of the fracture as a partial decompression. To evaluate fine motor movements, picking up a small object with toes and following a rectangular path were used. Also, the gross motor movements, upper and lower proximal and distal muscle forces were measured.
Results160 patients including 133 men (83.1%) and 16.9% women (27) with 36±12 years mean age were included. The most fracture location was lumbar (53.1%), followed by the thoracic (43.1%) and fractures in both regions (3.8%). The most injured vertebras were L1 (27.5%) and T12 (18.8%). Six months later, 61.9% of patients had a good score for removing a small object with toe, of which 67.5% belonged to patients with<24 hours surgery (P=0.01). Also, RR for ability to follow a rectangle (P=0.017) and lower limit gross motor were significantly better in patients with<24 surgery (P=0.02). However, no significant difference was found between the two groups for improved sensations (P<0.05).
ConclusionThis study showed that decompression<24 hours in TSCI is associated with a significant improvement in lower fine movements.
Keywords: decompression, lumbar, spinal cord injury, thoracic wall, trauma -
Journal of Dentistry, Shiraz University of Medical Sciences, Volume:23 Issue: 2, Jun 2022, PP 238 -243
The treatment choice in the management of odontogenic cysts in the mixed dentition period depends upon the size, location of the cyst, the bone integrity of the cystic wall, and its proximity to vital structures. Enucleation is indicated with smaller cysts, achieved by careful removal of a complete cyst without rupturing the cystic lining. Marsupializationand decompression are the treatments of choice for larger cysts as it can help to preserve the tooth bud of the successor tooth and reduce morbidity. Marsupialization is achieved by opening and deroofing the cyst, and making the cystic lining continuous with the oral cavity or surrounding structures by suturing the edges of the incised mucosa to the cystic wall. This helps in maintaining the patency of the cystic lesion. In the decompression, a cylindrical device (drain) is placed in the lesion, which maintains communication between oral cavity to cystic lesion. This decreases the intracystic pressure and results in bone formation. We present two cases of odontogenic cyst in children, where we used a modified decompression technique. We developed a modified surgical stent with the use of a Hawley’s appliance, which led to cystic decompression, and eventual eruption of the successor tooth. Notably, this modified technique also reduced both patient discomfort and the number of clinical visits, making it an effective treatment option. The unique design of the appliance also acted as a space maintainer for the eruption of successor tooth, which is very critical in mixed dentition for future prevention of space loss and eventual malocclusion. The advantage of our design was its easy removal and insertion with minimal discomfort.
Keywords: Odontogenic cysts, Decompression, surgical, Dentition, Mixed, Splints, space maintenance, Orthodontics -
Introduction
Early decompression within the first 24 hours after spinal cord injury (SCI) is proposed in currentguidelines. However, the possible benefits of earlier decompression are unclear. Thus, the present meta-analysisaims to investigate the existing evidence regarding the efficacy of ultra-early decompression surgery (within 12hours after SCI) in improving patients’ neurological status.
MethodsA search was performed in Medline, Em-base, Scopus and Web of Science electronic databases, until the end of August 2021. Cohort studies and clinicaltrials were included in the present study. Exclusion criteria were absence of an early or late surgery group, fail-ure to report neurological status based on the American spinal injury association impairment scale (AIS) grade,failure to perform the surgery within the first 12 hours after SCI, and duplicate reports and review articles. Twoindependent reviewers performed data collection, and risk of bias and certainty of evidence assessments. Theoutcome was reported as odds ratio (OR) and 95% confidence interval (CI).
ResultsData from 16 articles, whichstudied 868 patients, were included. Compared to early or late decompression surgery, ultra-early decompres-sion surgery significantly improves patients’ neurological status (OR = 2.25; 95% CI: 1.41 to 3.58). However,ultra-early surgery in thoracolumbar injuries is not significantly more effective than early to late surgery. More-over, ultra-early surgery in patients with a baseline AIS A increases the chance of neurologic resolvent up to 3.86folds (OR=3.86; 95% CI: 1.50 to 9.91). Contrastingly, ultra-early surgery does not result in significant improve-ment compared to early to late surgery in patients with AIS B (OR = 1.32; 95% CI: 0.51 to 3.45), AIS C (OR = 1.83;95% CI: 0.72 to 4.64), and AIS D (OR = 0.99; 95% CI: 0.31 to 3.17).
ConclusionCurrent guidelines emphasizethat spinal decompression should be performed within 24 hours after SCI, regardless of injury severity and loca-tion. However, results of the present study demonstrated that certain considerations may be taken into accountwhen performing decompression surgery: 1) in patients with AIS A injury, decompression surgery should beperformed as soon as possible, since its efficacy in neurological improvement is 3.86 folds higher in the first 12hours after injury. 2) ultra-early decompression surgery in patients with cervical injury is more effective than inpatients with thoracic or lumbar injuries. 3) postponing decompression surgery to 24 hours in SCI patients withAIS B to D does not significantly affect the neurological outcome.
Keywords: Decompression, Surgical, Spinal Cord injuries, Neurological Rehabilitation -
Background and Importance:
Fracture-dislocation of the thoracic or lumbar spine (traumatic spondyloptosis) occurs in less than 5% of all spinal injuries mainly affecting the ventral direction.
Case PresentationA paraplegic young man was admitted to Shahid Kamyab Hospital in Mashhad City, Iran due to a motor vehicle accident. Computerized tomography (CT) showed a complete posterior dislocation of the T10 vertebral body on T9, with the superior articular processes of T9 bilaterally locked in the inferior endplate of T10 and complete fractures of the posterior elements.
ConclusionThe spinal dislocation was re-aligned by a combination of Harrington fixation and pedicular screws leading to spinal fusion. Six months after surgery, the patient was still paraplegic but the sensory symptoms in the lower extremities and clean intermittent catheterization improved.
Keywords: Complete fracture-dislocation, Decompression, Neurologicaldeficit, Harrington spinalfixation -
Introduction
Abdominal compartment syndrome (ACS) is a sustained intraabdominal pressure (IAP) of 20 mmHg or higher with new organ dysfunction. Decompression is required when IAP exceeds 25 mmHg even without evidence of organ dysfunction. Common abdominal surgical diseases and operations can be complicated by ACS, and clinicians should have the requisite capacity to detect and intervene early enough. Intensive care unit (ICU) care has traditionally been the mainstay of ACS management.
Case PresentationA 23-year-old male was referred with a combined mesh and Bogota bag anterior abdominal construct after a midline laparotomy 24 hours earlier, following which the abdominal wall could not be closed primarily without tension. This was the result of significant edema of the bowel and retroperitoneum. This patient, after adequate resuscitation, underwent a twostaged procedure, 6 days apart, to achieve skin closure. After an unremarkable skin healing, a mesh repair for the consequent incisional hernia was carried out 15 months later.
ConclusionsThis patient’s ACS was successfullymanaged in a non-ICU setting and could demonstrate the possibility of successfully managing selected cases of laparotomy-related ACS in low-resource settings without ICU facilities.
Keywords: Decompression, Intraabdominal Pressure, Laparotomy, Abdominal Compartment Syndrome -
Background
Seven to ten percent of facial nerve paralysis occurs in patients with temporal bone fracture. It has become increasingly common due to the development of human activity. One of the main topics of discussion is facial nerve injury management resulting from temporal bone trauma.The purpose of this study is to report the paralysis of facial nerve after temporal bone fractures.
AimIn this study, our goal was to record the facial profile of rhinoplasty applicants in Shiraz.
MethodsThis retrospective study analyzed 20 cases of traumatic paralysis of facial nerve, which underwent facial nerve decompression.
ResultsRecovery rate was correlated to the delay of surgery. 83.3% of patients who underwent decompression surgery within the first 2 weeks after trauma had an excellent therapeutic outcome (HB grading I-II) and the difference was statistically significant (p=0.000).
ConclusionFacial nerve paralysis surgical management after bone fracture is controversial. The decision must be taken according to the type of paralysis and the radiological electrophysiological and evolutionary data.
Keywords: Temporal bone, Facial nerve, Paralysis, Decompression, Surgery -
Management of a Large Periapical Lesion Using Decompression: A Case Report with Three-year Follow-up
Large radicular lesions should be treated initially by orthograde root canal therapy. When the signs and symptoms of the infection (e.g. persistent purulent drainage) do not resolve after this treatment, then surgical approaches should be considered. In the cases of large radicular cysts, total enucleation of the cyst can endanger adjacent structures and teeth. Therefore, decompression or marsupialization techniques are recommended in order to decrease the size of the lesion. In this case report, a 55-year-old woman with previously initiated therapy was referred to endodontic department for management of a sinus tract associated with tooth #7. Root canal treatment was performed and intracanal irrigant (5.25% sodium hypochlorite) activated using passive ultrasonic application, various intracanal medicament (calcium hydroxide, double antibiotic paste) was used in multiple sessions, but intracanal purulent drainage was not resolved. After this, decompression was performed using needle cap to maintain the opening of the cyst and remained for three months. During this period the cavity was kept clean and rinsed by the patient with 0.2% chlorhexidine mouthwash. After three-year follow-up, radiographic examination revealed substantial osseous repair of the defect and clinical signs and symptoms were absent.
Keywords: Antibacterial Agent, Antibiotic, Decompression, Periapical Lesion, Root Canal Treatment -
BackgroundAn oscillating bone saw is rarely used to perform laminectomy. The purpose of this study was to describea relatively quick and harmless technique for multilevel laminectomy in patients with lumbar spinal stenosis (LSS) usingan oscillating bone saw to find out how this instrument affects the time of surgery and rate of complications.MethodsThis prospective study was conducted on 45 patients with LSS who required multilevel laminectomy. Thebones were cut using an oscillating sagittal saw equipped with a fine 1-cm blade. Posterolateral fusion was performed ifany evidence of spinal instability occurred, or the correction of deformity was addressed. The time spent for laminectomyfrom initial cutting to the whole bone removal (T1) and the duration of laminectomy (i.e., from initiation to the end ofdecompression; T2) were recorded for the corresponding level. The volume of harvested autograft was also measured,and any dural injuries were reported.ResultsPosterolateral fusion was performed on 32 (71.1%) patients. The mean T1 and T2 per level were estimated at70.5±5.4 and 157.5±12.1 sec, respectively. In addition, the mean volume of harvested autograft per level was obtainedas 3.5±1.2 cc. No durotomy was observed during laminectomy using an oscillating bone saw. However, a dural tearoccurred in one patient when a Kerisson punch was utilized for ligamentum flavum removal and foraminotomy.ConclusionBased on the findings, it can be concluded that laminectomy by means of the oscillating bone saw is asafe procedure that provides a sufficient volume of harvested autograft for fusion. This technique could also induce aremarkable reduction in the time of surgery.Level of evidence: IVKeywords: decompression, laminectomy, lumbar spine, oscillating saw, Stenosis
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سابقه و هدف
کیست ادنتوژنیک کراتینیزه یک کیست ادنتوژنیک تکاملی است که عمدتا منشا آن دنتال لامینا می باشد. این کیست دارای ماهیت تهاجم موضعی و عود بالا می باشد.اقدامات درمانی متعددی جهت کنترل عود این کیست در مطالعات وجود دارد. یکی از روش های محافظه کارانه استفاده از ترکیب دو تکنیک انوکلیشن متعاقب دکامپرشن می باشد. هدف از این مطالعه بررسی درمان ترکیبی دکامپرشن و انوکلیشن به عنوان یک درمان قطعی با وجود پیگیری 3 ساله بیماری می باشد.
گزارش موردکیس مورد بررسی یک بیمار مرد 24 ساله با OKC سمت چپ مندیبل است که با روش دکامپرشن و انوکلیشن به همراه peripheral ostectomy و کاربرد پماد موضعی 5FU(5 flurouracil) به صورت قطعی درمان شده است.
نتیجه گیریبا وجود انتخابهای متعدد درمان OKC جراحان اغلب به دنبال درمان محافظه کارانه این کیست به روش دکامپرشن و انوکلیشن هستند چرا که موربیدیتی و عود روش نسبت به روش های دیگر کمتر گزارش شده است.
کلید واژگان: کیست ادنتوژنیک کراتینیزه، انوکلیشن، دکامپرشن، 5 فلورویوراسیل
BACKGROUNackground and aimKeratinized odontogenic cyst is a developmental odontogenic cyst that is mainly due to dental lamina. This cyst has the nature of local invasion and high recurrence. There are several therapeutic measures to control the recurrence of this cyst in studies. One of the conservative approaches is to use an enucleation followed by decompression techniques. The aim of this study was evaluation of the combined therapeutic approach of decompression and enucleation with 3 years follow up as the definite treatment.
Case Report: Case study is a 5-year-old male patient with left mandibular OKC who has been definitively treated with decompression and enucleation with peripheral ostectomy and use of 5FU (5 flurouracil) topical ointment.ConclusionDespite many options for OKC treatment, surgeons often seek conservative treatment of this cyst by decompression and enucleation because morbidity and recurrence are less reported than other methods.
Keywords: Odontogenic keratocyst, enucleation, decompression, 5 flurouracil -
Journal of Dentistry, Shiraz University of Medical Sciences, Volume:20 Issue: 3, Sep 2019, PP 145 -151
Various treatment modalities have been reported for keratocystic odontogenic tumors (KOT), with different recurrence rates. Marsupialization and decompression are two different conservative surgical techniques for the treatment of KOTs. This study aimed at comparing the recurrence rate between marsupialization and decompression in the treatment of KOTs with or without adjunctive treatments. This is a systematic review study. The research sources utilized were PubMed (MEDLINE), Google scholar, Ovid MEDLINE and Cochrane Library. The keywords which were selected based on Medical Subject Heading (MeSH) terms and PICOS criteria were odontogenic keratocyst, keratocyst odontogenic tumor AND marsupialization OR decompression OR cystectomy OR enucleation OR curettage. Statistical analyses were performed to compare the recurrence rate between marsupialization and decompression with or without adjunctive treatments, regarding various follow-up times. The number of subjects that underwent marsupialization was 182. There was a significant difference for the recurrence rate between the marsupialization and decompression groups without considering adjunctive treatments (p= 0.001). However, considering adjunctive treatments, there was no difference between marsupialization and the decompression groups (p= 0.18). It appears that decompression without any adjuvant treatment may have a lower recurrence rate than marsupialization. The recurrence rate was not different when enucleation or cystectomy was performed after decompression and marsupialization.
Keywords: Odontogenic cysts, Mandible, Decompression, Jaw Cysts -
Introduction
Despite the vast number of surveys, no consensus has been reached on the optimum timing of spinal decompression surgery. This systematic review and meta-analysis aimed to compare the effects of early and late spinal decompression surgery on neurologic improvement and post-surgical complications in patients with traumatic spinal cord injuries.
MethodsTwo independent reviewers carried out an extended search in electronic databases. Data of neurological outcome and post-surgery complication were extracted. Finally, pooled relative risk (RR) with a 95% confidence interval (CI) was reported for comparing of efficacy of early and late surgical decompression.
ResultsEventually 22 studies were included. The pooled RR was 0.77 (95% CI: 0.68-0.89) for at least one grade neurological improvement, and 0.84 (95% CI: 0.77-0.92) for at least two grade improvement. Pooled RR for surgical decompression performed within 12 hours after the injury was 0.26 (95% CI: 0.13-0.52; p<0.001), while it was 0.75 (95% CI: 0.63-0.90; p=0.002) when the procedure was performed within 24 hours, and 0.93 (95% CI: 0.76-1.14; p=0.48) when it was carried out in the first 72 hours after the injury. Surgical decompression performed within 24 hours after injury was found to be associated with significantly lower rates of post-surgical complications (RR=0.77; 95% CI: 0.68-0.86; p<0.001).
ConclusionThe findings of this study indicate that early spinal decompression surgery can improve neurologic recovery and is associated with less post-surgical complications. The optimum efficacy is observed when the procedure is performed within 12 hours of the injury.
Keywords: Decompression, Surgical, Early Surgical Decompression, Late Surgery, Injured Spinal Cord -
IntroductionBone cement leakage is the most common, however, it can have potentially disastrous complications during vertebroplasty and balloon kyphoplasty (BK). Polymethylmethacrylate (PMMA) is the most commonly used bone filler, however, calcium phosphate (CP) has been successfully used in spine surgery as a vertebral filler because it is not associated with exothermal reaction and is biologically very close to the vertebral bone. CP leakage during vertebral augmentation is extremely rare.Case PresentationA 72-year-old woman with an A2/AO type fracture of L1-vertebra underwent a transpedicular BK at the L1-vertebra with CP plus short segment pedicle screw construct (T12-L2) by minimally invasive surgery (MIS). Continuous neuromonitoring and fluoroscopy were used in this case, although no pathological signs were recorded because of the low radiopacity of CP. Two days later, incomplete paraplegia was presented due to intra and extradural cement leakage. The patient underwent an emergency T12-L2 wide decompression for removal of an epidural leak of CP plus durotomy for intradural CP removal. After removal of the cement, there was improvement of neurologic function. CP leakage should have occurred because of a violation of the medial right pedicle wall by the BK trockar and subsequently CP injection both intra and extradural. Since no direct intraoperative nerve root injury occurred, there was no pathologic sign during intraoperative neuromonitoring.ConclusionsPMMA leakage is well documented in the literature as a common complication during BK. Calcium phosphate leakage during vertebral augmentation is rare. Furthermore, delayed onset of neurologic deficit due to CP leakage has never been reported in the current literature. Spine surgeons and interventional radiologists should always be aware of this potential disastrous complication.Keywords: Calcium Phosphate Leakage, Ballon Kyphoplaty, Incomplete Paraplegia, Decompression, Durotomy, MIS Screw Fixation
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IntroductionLate-onset neurological impairment in unstable A3-A4/AO type thoracolumbar spinal fractures are rare, particularly if they are misdiagnosed as stable (25%). We present two neglected unstable burst fractures, who presented delayed trauma with neurologic deficit.Case PresentationCase 1: A 62-year-old male, who sought our department three months after trauma claiming neurogenic claudication, following fracture of L2.
Case 2: A 50-year old male, who had a jerky fall from his vehicle with subsequent back pain for a few days. One-month after the trauma he presented urinary retention.ConclusionsUnstable thoracolumbar A4 /AO type fractures, if left untreated or misdiagnosed, lead to vertebral body fragments retropulsed to the spinal canal under axial and bending forces resulting in progressively increased encroachment of the canal and finally compression on to cauda equina. Early recognition of an unstable A3-A4 /AO-type thoracolumbar fracture with C/T scan is mandatory along with appropriate treatment. This should be done in all cases, even in these without any neurological deficit and these with «normal» plain X-rays, because misdiagnosis and late onset neurological deficit is always a possibility. Physicians should be aware of this complication when treating thoracolumbar spine injuries with minor or absent symptoms and physiological neurologic findings.Keywords: Thoracolumbar A3, A4, Type Fracture, Late Onset Neurologic Deficits, Decompression, Stabilization, MRI or C, T Scan -
IntroductionTraumatic spinal cord injury (SCI) is a catastrophic event for patients with neurologic deficit and for the society in terms of economic issues. The prevalence of SCI seems to be increasing. There is not enough evidence regarding late neurologic decompression in patients with spinal cord injury.Case PresentationHere, we report on two patients with spinal cord injury, who were referred to our department after several days of trauma and both underwent decompression and posterior instrumented fusion (posterolateral decompression ) with favorable results.ConclusionsIt seems that late neurologic decompression might have some benefits for patients with SCI.Keywords: Spinal Cord Injury, Trauma, Thoracolumbar, Fracture, Late, Early, Decompression
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مقدمهدر سطح جهانی، مطالعات اندکی در مورد روش ارجح زمان بندی جراحی گردن و کمر در بیماران مبتلا به درگیری هم زمان ستون فقرات گردنی و کمری با فرایندهای دژنراتیو از قبیل تنگی کانال هم زمان کمری و گردنی انجام شده است که اغلب این مطالعات، گذشته نگر هستند. از این رو، کارآزمایی بالینی حاضر، با هدف مقایسه ی پیامدها و عوارض عمل جراحی یک مرحله ای با دو مرحله ای طراحی گردید.روش هامطالعه ی حاضر یک کار آزمایی بالینی بود. 20 بیمار مبتلا به تنگی هم زمان فقرات گردنی و کمری که بر اساس معیارهای بالینی نیازمند مداخله ی الزامی جراحی روی هر دو ناحیه ی گردنی و کمری بودند، به صورت تصادفی به دو گروه تقسیم شدند. در گروه یک مرحله ای، رفع فشار، وسیله گذاری و جوش دهی ستون فقرات گردنی و کمری به صورت هم زمان و طی یک عمل توسط دو تیم جراح انجام شد. در بیماران گروه دو مرحله ای، جراحی های گردن و کمر به صورت جداگانه و طی دو عمل مجزا انجام شد. خونریزی حین عمل، تعداد واحد گلبول قرمز ترانسفیوژن شده ی حین و بعد از عمل، مجموع زمان عمل، زمان ریکاوری، روزهای بستری در بیمارستان، مجموع هزینه ها و عوارض بعد از عمل میان دو گروه مقایسه شد. همچنین، نتایج بهبود بالینی اولیه در پایان ماه اول پس از اعمال جراحی با استفاده از پرسش نامه ی گردنی و کمری Oswestry میان دو گروه ارزیابی شد. از آزمون های t، 2χ و همبستگی Pearson جهت آنالیز داده ها استفاده شد.یافته هازمان عمل، زمان ریکاوری، تعداد روزهای بستری در بیمارستان و هزینه های کلی در گروه یک مرحله ای، به شکل معنی داری کاهش یافته بود. اختلاف آماری معنی داری میان دو گروه از لحاظ میزان خونریزی حین عمل، تعداد واحد خون تزریق شده و عوارض بعد از عمل وجود نداشت. نتایج بهبود بالینی اولیه، پس از اعمال جراحی در دو گروه یکسان بود (05/0 < P).نتیجه گیریانجام عمل به شیوه ی یک مرحله ای در صورت اجازه ی شرایط عمومی بیمار و وجود امکانات و تیم های مجرب جراحی، نتایج بالینی قابل مقایسه ای با روش دو مرحله ای دارد و عوارض بالقوه و خطرات بیشتری نیز ندارد.کلید واژگان: تنگی کانال هم زمان ستون فقرات کمری و گردنی، یک مرحله ای، دو مرحله ای، جراحی رفع فشار، وسیله گذاری و جوش دهیBackgroundCoexistent involvement of cervical and lumbar spine with destructive spondylotic degenerative processes such as tandem spinal stenosis (TSS) can be managed with simultaneous or staged decompressions; though, a controversy exists regarding the surgical staging strategy and limited research is available on its operative management which are mostly retrospective. This randomized clinical trial was conducted to compare outcomes of simultaneous decompression, fusion and instrumentation of cervical and lumbar spine versus 2-stage operations.MethodsTwenty patients with TSS were randomly assigned to either of two groups; in the 1-stage group, simultaneous decompression, fusion and instrumentation of both cervical and lumbar spine were performed by two teams in a single operation. The 2- stage group underwent staged cervical and lumbar surgeries in 2 separate operations. Combined blood loss, transfused packed cells, operation time, recovery time, days of hospitalization, overall expenses, Oswestry Disability Index (ODI) and complications were compared between the two groups. Student T-test, Chi-square test and Pearson correlation were used for analyzing the data.
Findings: Operation time, recovery time, days of hospitalization and overall expenses were significantly reduced in 1-stage surgery group. There were no significant differences between the two groups in terms of combined blood loss, transfused packed cells or postoperative complications. Early cervical and lumbar clinical outcomes which were evaluated by Oswestry neck and back disability index, respectively, were similar in two groups (P > 0.05).ConclusionSingle-stage surgery had comparable clinical outcomes compared to 2-stage operations without exposing the patients to unnecessary risks.Keywords: Tandem spinal stenosis, 1, stage, 2, stage, Decompression, Fusion, instrumentation surgery -
Prior animal models have shown that rats sustaining 3-second immediate spinal cord compression had significantly better functional recovery and smaller lesion volumes than rats subjected to compression times of 1 hour, 6 hours, 3 weeks, and 10 weeks after spinal cord injury. We compare locomotor rating scales and spinal cord histopathology after 3 seconds and 10 minute compression times.. Ten rats were assigned into two early (3-second) and late (10-minute) compressive surgery groups. Compressive injury was produced using an aneurysmal clip method. Rats were followed-up for 11 weeks, and behavioral assessment was done by inclined plane test and tail-flick reflex. At the end of the study, the rats were sacrificed, and spinal cord specimens were studied in light and EM. Basso, Beattie and Bresnahan (BBB) locomotor rating scales were significantly better in the early compression group after the 4th week of evaluation (P<0.05) and persisted throughout the remainder of the study. Histopathology demonstrated decreased normal tissue, more severe gliosis and cystic formation in the late group compared to the early group (P<0.05). In EM study, injuries in the late group including injury to the myelin and axon were more severe than the early compression group, and there was more cytoplasmic edema in the late compression group. Spinal cord injury secondary to 3-second compression improves functional motor recovery, spares more functional tissue, and is associated with less intracellular edema, less myelin and axon damage and more myelin regeneration in rats compared to those with 10 minutes of compression. Inclined plane test and tail-flick reflex had no significant difference.Keywords: BBB, Decompression, Electron microscopy, Histopathology, Spinal cord injury
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سابقه و هدفبیماری برداشت فشار اولین بار در1850 در غواصان و کارگران معدنی که با هوای فشرده کار می کردند دیده شد و تا 1930 تعریف درستی برای آن ارائه نگردید. این بیماری به نام های چون Bend، Aeropathy، Aeroembolism، Dysbarism، DCI/DCS نیز خوانده می شود.
عمده مشکلاتی که در زمان صعود به ارتفاعات و به سطح آب با آن مواجه می شوند تغییراتی است که در حجم گاز موجود در حفرات بدن رخ می دهد. هدف از ارائه این مطالعه جمع آوری خلاصه اطلاعات مفید مرتبط با بیماری برداشت فشار و برخورد با بیماران جهت استفاده عملیاتی همکاران می باشد.یافته هامخاطرات اصلی ایجاد شده در بیماری برداشت فشار مبتنی بر قانون هنری و شامل اثرات مخرب ناشی از آزاد شدن گاز های موجود در مایعات بدن بوده که مهم ترین آن گاز نیتروژن است. در بدن بافت چربی دارای نیتروژن بیشتری بوده لذا افراد چاق دارای استعداد بالاتری جهت ابتلا به این بیماری می باشند. این بیماری دارای علائم متعددی بوده لذا تشخیص آن با رد سایر بیماری ها مقدور می باشد.
اتیولوژی بیماری کاهش ناگهانی فشار بارومتریک محیطی و آزاد شدن گاز های محلول در مایعات بدن است. پاتوفیزیولوژی بیماری شامل سه مکانیسم مختلف است که به آسیب بافتی می انجامد: 1- انهدام سلول ها بدن توسط حباب های آزاد شده، 2- انسداد مکانیکی عروق و 3- اثر فشاری حباب ها یا آمبولی گازی بر عروق و اعصاب مجاور.بحث و نتیجه گیریبه دلیل گسترش روز افزون دریانوردی و هوانوردی لزوم اطلاع کافی در خصوص علائم، تشخیص سریع، برخورد لازم و پیشگیری مناسب این بیماری برای کلیه گروه ها خصوصا هوانوردان، دریانوردان و گروه پزشکی و درمانی ضروری به نظر می رسد.
کلید واژگان: برداشت فشار، هوانوردی، بیماری برداشت فشارBackgroundSince 1850، as the first time، DCS have been detected in divers and pitmen. There were no appropriate explanation for this Illness until 1930. Other names such as Bend، Aeropathy، Aeroembolism، Dysbarism، DCI/DCS were used. At the ascend to height، most of the problems which occur due to changing the pressure of the body cavities. The goal of this presentation is collection of the abstract and sufficient information for use our colleagues.ResultsThe major adventures were happen in DCS is based on henry’s law and consist of any hazardous would be occur in result of every soluble gas molecules egress the body’s fluid which nitrogen is one of the most important of these gases. Obese individuals are more susceptible، because fat tissue have very amount of nitrogen. DCS have different features and net diagnoses were possible by rule out of other diseases. The etiology of this sickness is the sudden reduction in barometric pressure and the release of soluble gases in body fluids. The pathophysiology of this sickness is consist of three different mechanisms which result in tissue damage: 1) destruction of tissue cells by released gases، 2) mechanical obstruction of blood vessels and 3) pressing effect of bubbles or emboli’s on adjacent vessels and nerves.ConclusionBecause of the daily development of aviation and seafaring، inform about DCS and its complications، prevention and treatment for all population especially aviators، divers and medical groups are necessary.Keywords: Decompression, Aviation, Decompression Sickness -
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زمینهمرور مقالات مرتبط با سلول های بنیادی نشان می دهند که این عوامل بر کاهش درد و تاخیر در پیشرفت استئونکروز سر فمور در مراحل اولیه تاثیر دارند. در این مطالعه اثربخشی درمان به وسیله ایجاد تونل استخوانی و کاشت مغز استخوان اتولوگ تغلیظ شده در مراحل اولیه بررسی شد.
مواد و روش هامطالعه به صورت کارآزمایی بالینی تصادفی انجام شد. تعداد 28 هیپ در مراحل اولیه استئونکروز به دو گروه 14 تایی تقسیم شدند و در همگی تونل استخوانی ایجاد گردید. در گروه گرافت مغز استخوان تزریق سلول های تک هسته ای مغز استخوان اتولوگ نیز انجام شد. بیماران و افراد ارزیابی کننده نسبت به تعیین گروه درمان ناآگاه بودند. مدت پیگیری 24 ماه بود و در پایان دوره بیماران با مقیاس «وومک» (WOMAC)، مقیاس سنجش دیداری درد (VAS) و ام آرآی ارزیابی شدند.
یافته هانتایج نشان دادند تفاوت میانگین و روند تغییرات نمرات در مقیاس های «وومک» و سنجش دیداری درد 24 ماه پس از عمل جراحی بین دو گروه از نظر آماری معنی دار بود (001/0>p). تغییرات نتایج ام آرآی در گروه گرافت در جهت بهبودی (046/0=p) و در گروه دیگر در جهت تخریب (001/0>p) معنی دار بود. سه مورد از 14 بیمار در گروه گرافت پسرفت بیماری داشتند.
نتیجه گیریتزریق مغز استخوان تغلیظ شده در ناحیه نکروتیک می تواند درمان موثری در مراحل اولیه استئونکروز سر فمور باشد و باعث کاهش درد و علایم مفصلی و همچنین تاخیر در پیشرفت بیماری و حتی کاهش مرحله استئونکروز گردد.
کلید واژگان: استئونکروز، گردن فمور، سلول پایه، دکمپرسیونBackgroundThe use of stem cell is believed to reduce pain and delay the deterioration in the early stages of femoral head osteonecrosis. The aim of this study was to evaluate the effect of autologus concentrated mononuclear bone marrow cell implantation after core decompression in femoral heads that were in the early stages of osteonecrosis.
MethodsTwenty eight femoral heads with osteonecrosis that were undergoing core decompression were randomly divided into two groups of 14. One group received additional implantation of autologus bone marrow mononuclear cells. The two groups were، then evaluated within 2 years with WOMAC (Western Ontario and McMaster University osteoarthritis index)، visual analogue pain index (VAS) and MRI of the femoral heads.
ResultsA significant improvement in WOMAC، and VAS scores was observed within the 2 years of follow-up in the implanted group، compared to the control group (p<. 001). The MRI findings were also significantly better in the implanted group (p=. 046)، with 3 cases showing change to a lower osteonecrosis stage. The control group، on the other hand، showed worsening in the osteonecrotic heads (p<. 001).
ConclusionsImplantation of concentrated bone marrow mononuclear cell in the femoral heads undergoing core decompression in the early stages of osteonecrosis can reduce symptoms، and improve staging of osteonecrosis، better than core decompression alone.
Keywords: Osteonecrosis, Femur neck, Stem cells, Decompression
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