Intraocular Lymphoma: A Case Report

To report a patient with an intraocular lymphoma with history of treated brain lymphoma.Case Report: A 45-year-old female was referred with moderate chronic intermediate uveitis of both eyes that was unresponsive to medications. She had history of treated brain lymphoma with chemotherapy and radiotherapy 6 years before presentation. Systemic workup, laboratory evaluation, brain and orbital MRI was normal. 25-G pars plana vitrectomy with 400 intravitreal injection of methotrexate was done in both eyes. Intraocular lymphoma was reported by cytopathologic evaluation of vitreous fluid. Intraocular lymphoma should be kept in mind in a patient with persistant chronic and diffuse uveitis and vitritis specially when beginning over fifties, in order to select appropriate diagnostic and therapeutic measures.