Epidemiologic Characteristics of Premature Coronary Artery Disease among Patients who Underwent Coronary Artery Bypass Grafting

Back ground: Coronary artery disease (CAD) is commonly seen in patients older than 50 years old. The purpose of this study was to evaluate demographic variables and risk factors among patients with premature coronary artery disease (PCAD) who were candidate of coronary artery bypass grafting. In this retrospective study which was conducted in Baqiyatallah hospital in Tehran, from March 2005 to March 2007, 83 patients with angiographically proved CAD were included; PCAD defined as CAD under the age of 45 in males and 55 in females. There were 48 (57.8%) males and 35 (42.2%) females. The mean age of patients was 45.6 years (range, 31 to 55). Hyperlipidemia (70 cases, 84.3%) and hypertension (67 cases, 80.7%) were the most common detected risk factors. Fifty-one patients (61.4%) had three-vessel disease. Significant difference was seen between two genders in term of smoking and diabetes (P < 0.05). By earlier diagnosis of hyperlipidemia and hypertension in young population, premature coronary artery disease should be prevented.