Comparison of Blood loss in Septorhinoplasty with two different Anesthetic Technique; Propofol or Isoflurane

Bleeding during nasal operations is a determinant factor in surgical outcome، thus any method that could decrease blood loss during this surgery will be valuable. So this study was conducted to compare the amount of blood loss in septorhinoplasty with two different anesthetic technique; propofol or isoflurane. In this prospective randomized clinical trial، 60 patients with ASA physical class I & II، scheduled for septorhinoplasty were studied. Patients were randomly allocated into two groups (30 patients in each group). After similar induction of anesthesia in all patients، in Group I; propofol with remifentanil، and in Group II; isoflurane with remifentanil used for maintenance of anesthesia. The bleeding، surgeons'' satisfaction from surgical field and also hemodynamic parameters was noted and compared with SPSS statistical software between two groups across the study. The demographic parameters، surgical and anesthesia related factors were similar in both groups. The mean blood loss volume was less in propofol group (35. 3 ± 18. 8 ml) than isoflurane (91 ± 18. 3 ml) group significantly (p<0/001). Surgeon satisfaction was higher in propofol group too (p<0/01). Hemodynamic parameters such as heart rate، systolic and diastolic blood pressure and SPO2 were comparable between two groups (except in a few short intervals). It may be concluded that anesthesia with Propofol (TIVA) may result in decreased blood loss and higher surgeons satisfaction in septorhinoplasty compared with isoflurane anesthesia.