PYY (3-36) Gene Responses to Treadmill Running with or without Pistachio-Atlantica in Female Rats

Intrudaction: PYY (3-36) has an important role in satiety; reduce food intake and regulation of energy homeostasis. The aim of this study was to determine the small intestine and kidney PYY (3-36) relative gene expression in response to treadmill-running training in female rats. Twenty female wistarrats (6-8 weeks oldand 125-135 g weight) were used. Animals were randomly assigned into saline-control (SC), saline-training (ST), and Baneh-control (BC), and Baneh-training (BT). Training groups were given exercise on a motor-driven treadmill at 25 m/min (0% grade) for 60 min/dayand5 days/week for eight weeks. Subjects were fed orally, withBaneh extraction and saline for four weeks. PYY (3-36) relative gene expression was detected by Real-time PCR method. Results demonstrated that Baneh extraction significantly increases PYY (3-36) relative gene expression in small intestine (P < 0.013) and kidney (P < 0.025).Also exercise reduces PYY (3-36) relative gene expression in and kidney (P < 0.03). Discussion and Exercise training decreases PYY (3-36) relative gene expression in small intestine and kidney