Effects of hazelnut consumption on fasting blood sugar, total antioxidant capacity, hs-CRP and paraoxonase-1 activity in patients with type 2 diabetes

Diabetes is associated with increased inflammatory biomarkers and decreased paraoxonase-1 activity and total antioxidant capacity. The aim of this study was to evaluate the effect of hazelnut on hs-CRP, total antioxidant capacity and paraoxonase-1 activity in type 2 diabetes.

In an 8-week randomized clinical trial, 50 patients were assigned to either the control or intervention groups. Hazelnuts replaced 10% of total daily calorie intake in the intervention group. Blood samples were obtained at the start and at the end of week 8. Dietary data were obtained using 24-dietary recall and were analyzed by Nutritionist IV software. All data were analyzed by SPSS version 15.

Compared with baseline, total antioxidant capacity decreased in both groups, but at the end of the study, there were no statistical differences between two groups. Also, no differences were observed in Fasting blood sugar (FBS), paraoxonase-1 activity and hs-CRP levels.

Hazelnuts consumption had no effect on FBS, hs-CRP, total antioxidant capacity and paraoxonase-1 activity in type 2 diabetic patients.