omparison of intravenous and intraosseous anesthesia in animal models

Various methods are used for inducing anesthesia. This study comparedintravenous and intraosseous propofol anesthesia in the animal model. 12 healthy adult cats (5male and 7 female) in two groups, intravenous (IV) and intraosseous (IO) were studied. In both IV and IO groups 8 mg propofol per kg body weight was injected. Heart rate, respiratory rate, pulse rate,rectal temperature, ETCo2, SPO2, quality of anesthesia and recovery were evaluated and recorded before and after injection of propofol in 0,5, 10, 15, 20, 25 and 30 minutes. Independent t test was used and a p value < 0.05 was considered to be significant. The average recovery time in the (IV)method was 52/5±9/72 minutes and in the (IO)method 26/14±90 minutes and there was no ignificant difference for recovery time (p= 0/549).Information about depth of anesthesia (p= 0/1171) and quality of recovery (p=0/3404) were found to have no significant difference p >(0/05). Satisfactory results were recorded in anesthesia with propofol in both intravenous and intraosseous groups. Intraosseous anesthesia is desirable and faster in emergency situations in and cases with difficult vascular access.