The Effect of NaF Mouthrinse, GC Tooth Mousse and GC MI Paste Plus on White Spot Inhibition: An Invitro Study

To compare the effects of 0.05% sodium fluoride (NaF) mouthrinse, GC Tooth Mousse and GC MI Paste Plus on white spot formation inhibition. Thirty pairs of extracted human premolars were cut in half mesio-distally with a disc. The teeth were coated with nail varnish, except a part of the buccal and/or lingual enamel, which was used as the test area, and then divided into 4 groups randomly: A) control, B) 0.05% NaFmouthrinse, C) Tooth Mousse, D) MI Paste Plus. Therapeutic agents were applied once daily following the manufacturer’s directions in a PH-cycling model over 35 days. At the end of the experiment, all the specimens were examined in order to detect white spot formation before and after drying (scoring 0-2). Mann Whitney test was used for statistical analysis. The mean of the white spot scores in groups B (0.16), C (1.4) and D (1.2) were significantly lower than group A (2). Significantly lower mean of white spot scores was found in NaFmouthrinse group compared with two other products. No significant difference was observed between Tooth Mousse and MI Paste Plus. Although 0.05% NaF mouthrinse, GC Tooth Mousse and GC MI Paste Plus are effective preparations to inhibit white spot formation, NaFmouthrinse has better efficacy than CPP-ACP (casein phosphopeptide-amorphous calcium phosphate) products.